CLINICAL ASPECTS AND BIOCHEMICAL MARKERS OF BONE FORMATION AFTER LIVER TRANSPLANTATION

Biochemical markers of bone formation [osteocalcin (OC), N-terminal propeptid of type 1 procollagen (P1NP), bone isoferment of alkaline phosphatase (BALP)] were estimated in 34 recipients after liver transplantation. Three types of deviation have been demonstrated: combination elevated circulating l...

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Main Authors: V.P. Buzulina, I.A. Pronchenko, I.P. Yermakova, M.N. Kornilov, E.B. Yaroshenko, D.S. Mnatsakanyan, T.K. Koliashvili, N.P. Shmerko
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2012-03-01
Series:Вестник трансплантологии и искусственных органов
Subjects:
Online Access:https://journal.transpl.ru/vtio/article/view/108
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author V.P. Buzulina
I.A. Pronchenko
I.P. Yermakova
M.N. Kornilov
E.B. Yaroshenko
D.S. Mnatsakanyan
T.K. Koliashvili
N.P. Shmerko
author_facet V.P. Buzulina
I.A. Pronchenko
I.P. Yermakova
M.N. Kornilov
E.B. Yaroshenko
D.S. Mnatsakanyan
T.K. Koliashvili
N.P. Shmerko
author_sort V.P. Buzulina
collection DOAJ
description Biochemical markers of bone formation [osteocalcin (OC), N-terminal propeptid of type 1 procollagen (P1NP), bone isoferment of alkaline phosphatase (BALP)] were estimated in 34 recipients after liver transplantation. Three types of deviation have been demonstrated: combination elevated circulating levels OC and P1NP with normal levels BALP in recipients without clinical postoperative complication; combination lower levels OC and BALP with normal levels P1NP in recipients as a result of corticosteroid therapy prior/ following transplantation; superior levels P1NP with normal levels OC and BALP which results excessive accumulation hepatic collagen formation in recipients with postoperative clinical complication.
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spelling doaj.art-3711703796fd4132ad83e6793879395f2024-11-26T12:09:34ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912012-03-01141192610.15825/1995-1191-2012-1-19-2651CLINICAL ASPECTS AND BIOCHEMICAL MARKERS OF BONE FORMATION AFTER LIVER TRANSPLANTATIONV.P. Buzulina0I.A. Pronchenko1I.P. Yermakova2M.N. Kornilov3E.B. Yaroshenko4D.S. Mnatsakanyan5T.K. Koliashvili6N.P. Shmerko7Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowBiochemical markers of bone formation [osteocalcin (OC), N-terminal propeptid of type 1 procollagen (P1NP), bone isoferment of alkaline phosphatase (BALP)] were estimated in 34 recipients after liver transplantation. Three types of deviation have been demonstrated: combination elevated circulating levels OC and P1NP with normal levels BALP in recipients without clinical postoperative complication; combination lower levels OC and BALP with normal levels P1NP in recipients as a result of corticosteroid therapy prior/ following transplantation; superior levels P1NP with normal levels OC and BALP which results excessive accumulation hepatic collagen formation in recipients with postoperative clinical complication.https://journal.transpl.ru/vtio/article/view/108orthotropic liver transplantation, biochemical markers of bone formation, bone mineral density.
spellingShingle V.P. Buzulina
I.A. Pronchenko
I.P. Yermakova
M.N. Kornilov
E.B. Yaroshenko
D.S. Mnatsakanyan
T.K. Koliashvili
N.P. Shmerko
CLINICAL ASPECTS AND BIOCHEMICAL MARKERS OF BONE FORMATION AFTER LIVER TRANSPLANTATION
Вестник трансплантологии и искусственных органов
orthotropic liver transplantation, biochemical markers of bone formation, bone mineral density.
title CLINICAL ASPECTS AND BIOCHEMICAL MARKERS OF BONE FORMATION AFTER LIVER TRANSPLANTATION
title_full CLINICAL ASPECTS AND BIOCHEMICAL MARKERS OF BONE FORMATION AFTER LIVER TRANSPLANTATION
title_fullStr CLINICAL ASPECTS AND BIOCHEMICAL MARKERS OF BONE FORMATION AFTER LIVER TRANSPLANTATION
title_full_unstemmed CLINICAL ASPECTS AND BIOCHEMICAL MARKERS OF BONE FORMATION AFTER LIVER TRANSPLANTATION
title_short CLINICAL ASPECTS AND BIOCHEMICAL MARKERS OF BONE FORMATION AFTER LIVER TRANSPLANTATION
title_sort clinical aspects and biochemical markers of bone formation after liver transplantation
topic orthotropic liver transplantation, biochemical markers of bone formation, bone mineral density.
url https://journal.transpl.ru/vtio/article/view/108
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