Tumor-derived interleukin-1α and leukemia inhibitory factor promote extramedullary hematopoiesis.

Tumor-derived interleukin-1α and leukemia inhibitory factor promote extramedullary hematopoiesis.

Extramedullary hematopoiesis (EMH) expands hematopoietic capacity outside of the bone marrow in response to inflammatory conditions, including infections and cancer. Because of its inducible nature, EMH offers a unique opportunity to study the interaction between hematopoietic stem and progenitor ce...

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Bibliographic Details
Main Authors: Derek A G Barisas, Ashraf Ul Kabir, Jun Wu, Karen Krchma, Minseo Kim, Madhav Subramanian, Bernd H Zinselmeyer, Colin L Stewart, Kyunghee Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001746

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