Arterial Stiffness, Body Mass Index and Cardiovascular Disease Risk in Chinese Females at Various Ages
Background: This study investigated the correlation in parameters of arterial stiffness and cardiovascular disease (CVD) risk on age and body mass index (BMI) in Chinese females. Methods: This cross-sectional study enrolled 2220 females. Arterial stiffness was assessed by the measurement of arterial...
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IMR Press
2023-05-01
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| Series: | Reviews in Cardiovascular Medicine |
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| Online Access: | https://www.imrpress.com/journal/RCM/24/5/10.31083/j.rcm2405144 |
| _version_ | 1797814466102951936 |
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| author | Lin Jin Yichao Du Mengjiao Zhang Jianxiong Chen Lei Sha Mengmeng Cao Lanyue Tong Qingqing Chen Cuiqin Shen Lianfang Du Dingqian Wang Zhaojun Li |
| author_facet | Lin Jin Yichao Du Mengjiao Zhang Jianxiong Chen Lei Sha Mengmeng Cao Lanyue Tong Qingqing Chen Cuiqin Shen Lianfang Du Dingqian Wang Zhaojun Li |
| author_sort | Lin Jin |
| collection | DOAJ |
| description | Background: This study investigated the correlation in parameters of arterial stiffness and cardiovascular disease (CVD) risk on age and body mass index (BMI) in Chinese females. Methods: This cross-sectional study enrolled 2220 females. Arterial stiffness was assessed by the measurement of arterial velocity pulse index (AVI) and arterial pressure volume index (API). Individual 10-year cardiovascular risk was calculated for each patient using the Framingham cardiovascular risk score (FCVRS). Results: API and AVI had a significant J-shaped relationship with age. Beginning at the age of 30 years, the API started to increase, while after 49 years, the increase in API was even steeper. AVI increased from the age of 32 years, and increased more rapidly after 56 years. The linear association between API and BMI following adjustment for age was significant (β = 0.324, 95% CI 0.247–0.400, p < 0.001). In the total study cohort, FCVRS scores increased by 0.16 scores for every 1 kg/m2 increase in BMI and by 0.11 scores for each 1 value increase in API in the age adjusted model. Conclusions: API and BMI correlate with 10-year cardiovascular risk at various ages in females. Regardless of age, overweight females have a higher risk of increased API. Therefore API can be used for the early detection of CVD so that preventive therapy can be instituted in these high risk patients. Clinical Trial Registration: Registered on the official website of the China Clinical Trial Registration Center (20/08/2020, ChiCTR2000035937). |
| first_indexed | 2024-03-13T08:08:08Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 1530-6550 |
| language | English |
| last_indexed | 2024-03-13T08:08:08Z |
| publishDate | 2023-05-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Reviews in Cardiovascular Medicine |
| spelling | doaj.art-37118c472ea24706a8b18e878462e5d42023-06-01T01:35:07ZengIMR PressReviews in Cardiovascular Medicine1530-65502023-05-0124514410.31083/j.rcm2405144S1530-6550(23)00857-8Arterial Stiffness, Body Mass Index and Cardiovascular Disease Risk in Chinese Females at Various AgesLin Jin0Yichao Du1Mengjiao Zhang2Jianxiong Chen3Lei Sha4Mengmeng Cao5Lanyue Tong6Qingqing Chen7Cuiqin Shen8Lianfang Du9Dingqian Wang10Zhaojun Li11Department of Ultrasound, Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 200052 Shanghai, ChinaDepartment of Neurosurgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 200080 Shanghai, ChinaDepartment of Medical Imaging, Weifang Medical University, 261053 Weifang, Shandong, ChinaDepartment of Ultrasound, Mindong Hospital Affiliated to Fujian Medical University, 355000 Ningde, Fujian, ChinaDepartment of Ultrasound, Shanghai General Hospital Jiading Branch, Shanghai Jiaotong University School of Medicine, 201812 Shanghai, ChinaDepartment of Ultrasound, Shanghai General Hospital Jiading Branch, Shanghai Jiaotong University School of Medicine, 201812 Shanghai, ChinaDepartment of Ultrasound, Shanghai General Hospital Jiading Branch, Shanghai Jiaotong University School of Medicine, 201812 Shanghai, ChinaDepartment of Ultrasound, Shanghai General Hospital Jiading Branch, Shanghai Jiaotong University School of Medicine, 201812 Shanghai, ChinaDepartment of Ultrasound, Shanghai General Hospital Jiading Branch, Shanghai Jiaotong University School of Medicine, 201812 Shanghai, ChinaDepartment of Ultrasound, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 200080 Shanghai, ChinaSchool of Informatics, College of Science & Engineering, The University of Edinburgh, EH8 9AB Edinburgh, UKDepartment of Ultrasound, Shanghai General Hospital Jiading Branch, Shanghai Jiaotong University School of Medicine, 201812 Shanghai, ChinaBackground: This study investigated the correlation in parameters of arterial stiffness and cardiovascular disease (CVD) risk on age and body mass index (BMI) in Chinese females. Methods: This cross-sectional study enrolled 2220 females. Arterial stiffness was assessed by the measurement of arterial velocity pulse index (AVI) and arterial pressure volume index (API). Individual 10-year cardiovascular risk was calculated for each patient using the Framingham cardiovascular risk score (FCVRS). Results: API and AVI had a significant J-shaped relationship with age. Beginning at the age of 30 years, the API started to increase, while after 49 years, the increase in API was even steeper. AVI increased from the age of 32 years, and increased more rapidly after 56 years. The linear association between API and BMI following adjustment for age was significant (β = 0.324, 95% CI 0.247–0.400, p < 0.001). In the total study cohort, FCVRS scores increased by 0.16 scores for every 1 kg/m2 increase in BMI and by 0.11 scores for each 1 value increase in API in the age adjusted model. Conclusions: API and BMI correlate with 10-year cardiovascular risk at various ages in females. Regardless of age, overweight females have a higher risk of increased API. Therefore API can be used for the early detection of CVD so that preventive therapy can be instituted in these high risk patients. Clinical Trial Registration: Registered on the official website of the China Clinical Trial Registration Center (20/08/2020, ChiCTR2000035937).https://www.imrpress.com/journal/RCM/24/5/10.31083/j.rcm2405144cardiovascular riskarterial stiffnesswomenagingbody mass index |
| spellingShingle | Lin Jin Yichao Du Mengjiao Zhang Jianxiong Chen Lei Sha Mengmeng Cao Lanyue Tong Qingqing Chen Cuiqin Shen Lianfang Du Dingqian Wang Zhaojun Li Arterial Stiffness, Body Mass Index and Cardiovascular Disease Risk in Chinese Females at Various Ages Reviews in Cardiovascular Medicine cardiovascular risk arterial stiffness women aging body mass index |
| title | Arterial Stiffness, Body Mass Index and Cardiovascular Disease Risk in Chinese Females at Various Ages |
| title_full | Arterial Stiffness, Body Mass Index and Cardiovascular Disease Risk in Chinese Females at Various Ages |
| title_fullStr | Arterial Stiffness, Body Mass Index and Cardiovascular Disease Risk in Chinese Females at Various Ages |
| title_full_unstemmed | Arterial Stiffness, Body Mass Index and Cardiovascular Disease Risk in Chinese Females at Various Ages |
| title_short | Arterial Stiffness, Body Mass Index and Cardiovascular Disease Risk in Chinese Females at Various Ages |
| title_sort | arterial stiffness body mass index and cardiovascular disease risk in chinese females at various ages |
| topic | cardiovascular risk arterial stiffness women aging body mass index |
| url | https://www.imrpress.com/journal/RCM/24/5/10.31083/j.rcm2405144 |
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