Evolutionary druggability for low-dimensional fitness landscapes toward new metrics for antimicrobial applications

The term ‘druggability’ describes the molecular properties of drugs or targets in pharmacological interventions and is commonly used in work involving drug development for clinical applications. There are no current analogues for this notion that quantify the drug-target interaction with respect to...

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Bibliographic Details
Main Authors: Rafael F Guerrero, Tandin Dorji, Ra'Mal M Harris, Matthew D Shoulders, C Brandon Ogbunugafor
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/88480