Trabecular bone deterioration in a postmenopausal female suffering multiple spontaneous vertebral fractures due to a delayed denosumab injection – A post-treatment re-initiation bone biopsy-based case study

Trabecular bone deterioration in a postmenopausal female suffering multiple spontaneous vertebral fractures due to a delayed denosumab injection – A post-treatment re-initiation bone biopsy-based case study

Background: Denosumab, is a potent anti-resorptive that, increases bone mineral density, and reduces fracture risk in osteoporotic patients. However, several case studies have reported multiple vertebral fractures in patients discontinuing denosumab. Case presentation: This case report describes a 6...

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Bibliographic Details
Main Authors: Louise Alstrup Drejer, Bilal Mohamad El-Masri, Charlotte Ejersted, Christina Møller Andreasen, Lisbeth Koch Thomsen, Jesper Skovhus Thomsen, Thomas Levin Andersen, Stinus Hansen
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Bone Reports
Subjects:
Osteoporosis
Denosumab
Bone histomorphometry
μCT
Bone remodeling
Rebound
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187223000517

Internet

http://www.sciencedirect.com/science/article/pii/S2352187223000517

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