Oral Chinese Herbal Medicine plus usual care for diabetic kidney disease: study protocol for a randomized, double-blind, placebo-controlled pilot trial

Oral Chinese Herbal Medicine plus usual care for diabetic kidney disease: study protocol for a randomized, double-blind, placebo-controlled pilot trial

BackgroundDiabetic kidney disease (DKD) has become the leading cause of kidney failure, causing a significant socioeconomic burden worldwide. The usual care for DKD fails to achieve satisfactory effects in delaying the persistent loss of renal function. A Chinese herbal medicine, Tangshen Qushi Form...

Full description

Bibliographic Details
Main Authors:	Meifang Liu, Yuan Ming Di, Lei Zhang, Lihong Yang, La Zhang, Junhui Chen, Ruobing Wang, Xiaoning Xie, Fang Lan, Liping Xie, Juan Huang, Anthony Lin Zhang, Charlie Changli Xue, Xusheng Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-02-01
Series:	Frontiers in Endocrinology
Subjects:	Chinese herbal medicine Tangshen Qushi Formula diabetic kidney disease randomized controlled trial semi-structured interview feasibility
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1334609/full

Similar Items

Tangshen Formula Alleviates Hepatic Steatosis by Inducing Autophagy Through the AMPK/SIRT1 Pathway
by: Yan Wang, et al.
Published: (2019-04-01)

Effect of Tangshen formula on the remodeling of small intestine and colon in Zucker diabetic fatty rats
by: Xin Yang, et al.
Published: (2023-10-01)

Tangshen formula improves diabetic nephropathy in STZ-induced diabetes rats fed with hyper-methionine by regulating the methylation status of kidney
by: Yongwei Jiang, et al.
Published: (2024-01-01)

Tangshen formula targets the gut microbiota to treat non-alcoholic fatty liver disease in HFD mice: A 16S rRNA and non-targeted metabolomics analyses
by: Shaopeng Wang, et al.
Published: (2024-04-01)

Renal-protective effects of Chinese medicinal herbs and compounds for diabetic kidney disease in animal models: protocol for systematic review and meta-analysis
by: Meifang Liu, et al.
Published: (2024-01-01)

Tangshen Formula Attenuates Diabetic Nephropathy by Promoting ABCA1-Mediated Renal Cholesterol Efflux in db/db Mice
by: Peng Liu, et al.
Published: (2018-04-01)

Network Pharmacology, Molecular Docking, and Experimental Verification to Reveal the Mitophagy-Associated Mechanism of Tangshen Formula in the Treatment of Diabetic Nephropathy
by: Chen Y, et al.
Published: (2024-02-01)

Tangshen Formula Improves Diabetes-Associated Myocardial Fibrosis by Inhibiting TGF-β/Smads and Wnt/β-Catenin Pathways
by: Lin Hu, et al.
Published: (2021-12-01)

The efficacy and safety of Chinese herbal medicine for mild cognitive impairment: a systematic review and meta-analysis of randomized placebo-controlled trials
by: Lingling Liu, et al.
Published: (2024-02-01)

TMT-Based Proteomic Analysis of Continuous Cropping Response in <i>Codonopsis tangshen</i> Oliv.
by: Xiaogang Jiang, et al.
Published: (2023-03-01)

Tangshen Formula Attenuates Diabetic Kidney Injury by Imparting Anti-pyroptotic Effects via the TXNIP-NLRP3-GSDMD Axis
by: Nan Li, et al.
Published: (2021-01-01)

Influence of Chinese Herbal Formula on Bone Characteristics of Cobb Broiler Chickens
by: Yong Liu, et al.
Published: (2022-10-01)

Effects of Qidi Tangshen granules and their separate prescriptions on podocytes in mice with diabetic nephropathy
by: Borui Yu, et al.
Published: (2022-01-01)

Protective Application of Chinese Herbal Compounds and Formulae in Intestinal Inflammation in Humans and Animals
by: Yang Yang, et al.
Published: (2023-09-01)

Effects of Continuous Cropping of <i>Codonopsis tangshen</i> on Rhizospheric Soil Bacterial Community as Determined by Pyrosequencing
by: Meide Zhang, et al.
Published: (2021-07-01)

Network Pharmacology-Based Investigation of the Molecular Mechanisms of the Chinese Herbal Formula Shenyi in the Treatment of Diabetic Nephropathy
by: Keng Chen, et al.
Published: (2022-06-01)

Tonic Herbs and Herbal Mixtures in Chinese Medicine
by: Thomas Efferth, et al.
Published: (2016-01-01)

Treating Acute EXacerbations of COPD with Chinese HerbAL MedIcine to aid AntiBiotic Use Reduction (EXCALIBUR): study protocol of a randomised double-blind, placebo-controlled feasibility trial
by: Xiao-Yang Hu, et al.
Published: (2022-12-01)

The efficacy and safety of Sanqi Qushi Granule in patients with idiopathic membranous nephropathy ——protocol of a multicenter, randomized control trial (SQ-AUTUMN)
by: Chuang Li, et al.
Published: (2023-04-01)

A Machine Learning Approach for Recommending Herbal Formulae with Enhanced Interpretability and Applicability
by: Won-Yung Lee, et al.
Published: (2022-10-01)

Sanqi Qushi Granule Alleviates Proteinuria and Podocyte Damage in NS Rat: A Network Pharmacology Study and in vivo Experimental Validation
by: Wang L, et al.
Published: (2023-06-01)

SHRIMP Zircon U-Pb Dating of Mid-Pleistocene Dacite and Discussion of Relative Problems
by: LI Lin-lin, et al.
Published: (2015-01-01)

Subacute toxicity and stability of Soshiho-tang, a traditional herbal formula, in Sprague–Dawley rats
by: Shin In Sik, et al.
Published: (2012-12-01)

The reporting quality of randomized controlled trials in Chinese herbal medicine (CHM) formulas for diabetes based on the consort statement and its extension for CHM formulas
by: Yan Liu, et al.
Published: (2024-01-01)

Current Status of Herbal Medicines in Chronic Liver Disease Therapy: The Biological Effects, Molecular Targets and Future Prospects
by: Ming Hong, et al.
Published: (2015-12-01)

Codonopsis tangshen Oliv. Amelioration Effect on Diabetic Kidney Disease Rats Induced by High Fat Diet Feeding Combined with Streptozotocin
by: Xian-Yuan Lu, et al.
Published: (2018-11-01)

Identification of Active Compounds From Yi Nationality Herbal Formula Wosi Influencing COX-2 and VCAM-1 Signaling
by: Ji-Zhong Zhang, et al.
Published: (2020-11-01)

Transcriptomic Analysis Provides Novel Insights into the Heat Stress-Induced Response in <i>Codonopsis tangshen</i>
by: Xiaogang Jiang, et al.
Published: (2023-01-01)

Qushi Huayu decoction ameliorates non-alcoholic fatty liver disease in rats by modulating gut microbiota and serum lipids
by: Yiming Ni, et al.
Published: (2023-10-01)

The effects of herbal formula PROVE 1, antibiotic and protein levels on growth performance of growing pigs
by: Ngampongsai, W., et al.
Published: (2007-05-01)

Traditional Chinese Medicine Strategy for Treating Major Depressive Disorder Based on a Famous Formulation-Baweixiaoyaosan
by: YONGWEI LIU, et al.
Published: (2023-05-01)

Efficacy of integrative medicine in deficiency of both qi and yin in the rat model of type 2 diabetes
by: Jing Zhao, et al.
Published: (2015-10-01)

Immunoenhancement Effects of the Herbal Formula Hemomine on Cyclophosphamide-Induced Immunosuppression in Mice
by: Hyemee Kim, et al.
Published: (2022-05-01)

Protection against γ ray-induced damage using herbal formulas
by: FU Haiying, et al.
Published: (2022-04-01)

Kampo (Traditional Japanese Herbal) Formulae for Treatment of Stomatitis and Oral Mucositis
by: Masataka Sunagawa, et al.
Published: (2018-12-01)

Herbal Formula SS-1 Increases Tear Secretion for Sjögren’s Syndrome
by: Ching-Mao Chang, et al.
Published: (2021-09-01)

Herbal formulas for detoxification and dredging collaterals in treating carotid atherosclerosis: a systematic review and meta-analysis
by: Leyi Zhang, et al.
Published: (2023-12-01)

Effects of the Chinese herbal formula San-Huang Gu-Ben Zhi-Ke treatment on stable chronic obstructive pulmonary disease: study protocol of a randomized, double-blind, placebo-controlled trial
by: Yaqi Zu, et al.
Published: (2019-11-01)

Treating acute exacerbations of COPD with Chinese herbal medicine to aid antibiotic use reduction (Excalibur): a randomised double-blind, placebo-controlled feasibility trial
by: Merlin L. Willcox, et al.
Published: (2023-09-01)

Current Status and Major Challenges to the Safety and Efficacy Presented by Chinese Herbal Medicine
by: Xian Zhou, et al.
Published: (2019-01-01)