VIP Promotes Recruitment of Tregs to the Uterine–Placental Interface During the Peri-Implantation Period to Sustain a Tolerogenic Microenvironment

VIP Promotes Recruitment of Tregs to the Uterine–Placental Interface During the Peri-Implantation Period to Sustain a Tolerogenic Microenvironment

Uterine receptivity and embryo implantation are two main processes that need a finely regulated balance between pro-inflammatory and tolerogenic mediators to allow a successful pregnancy. The neuroimmune peptide vasoactive intestinal peptide (VIP) is a key regulator, and it is involved in the induct...

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Bibliographic Details
Main Authors: Lucila Gallino, Vanesa Hauk, Laura Fernández, Elizabeth Soczewski, Soledad Gori, Esteban Grasso, Guillermina Calo, Nora Saraco, Esperanza Berensztein, James A. Waschek, Claudia Pérez Leirós, Rosanna Ramhorst
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
early pregnancy
tolerance
VIP
tregs
implantation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02907/full

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