Exploring the unusual: a testosterone-secreting ovarian tumor
Ovarian steroid cell tumors are rare, representing less than 0.1% of all ovarian neoplasms. Among the myriad causes of hirsutism, ovarian tumors account for 1% of the reported cases. We present the case of a 49-year-old parous postmenopausal woman who sought medical attention for hirsutism for 2 ye...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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University of São Paulo
2024-02-01
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| Series: | Autopsy and Case Reports |
| Subjects: | |
| Online Access: | https://www.revistas.usp.br/autopsy/article/view/222442 |
| _version_ | 1797294388625276928 |
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| author | Harpreet Kaur Neha Singh Sushma Bharti Gurwinder Kaur |
| author_facet | Harpreet Kaur Neha Singh Sushma Bharti Gurwinder Kaur |
| author_sort | Harpreet Kaur |
| collection | DOAJ |
| description |
Ovarian steroid cell tumors are rare, representing less than 0.1% of all ovarian neoplasms. Among the myriad causes of hirsutism, ovarian tumors account for 1% of the reported cases. We present the case of a 49-year-old parous postmenopausal woman who sought medical attention for hirsutism for 2 years. This case illustrates the unusual and interesting connection between rare ovarian pathology and the clinical manifestation of hirsutism in a postmenopausal patient. Her ultrasonography and MRI showed a right adnexal mass of solid-cystic consistency with thin septations. Her laboratory workup revealed high levels of total testosterone of 256 ng/ml (8.4-48.1ng/ml) and free testosterone of 7.36 pg/ml (0.2-4.1 pg/ml), while DHEAS - 234 µg/dl (35.4-256 µg/dl) and CA125 - 15.8U/L (0.0-35 U/L) were in the normal range. She underwent exploratory laparotomy with a total abdominal hysterectomy and oophorectomy. Histopathological examination and immunohistochemistry conclusively established the presence of a steroid cell tumor, specifically classified as "Not Otherwise Specified"(NOS), in the right ovary.
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| first_indexed | 2024-03-07T21:30:31Z |
| format | Article |
| id | doaj.art-372510a49e774919aa2aee45f69f51a2 |
| institution | Directory Open Access Journal |
| issn | 2236-1960 |
| language | English |
| last_indexed | 2024-03-07T21:30:31Z |
| publishDate | 2024-02-01 |
| publisher | University of São Paulo |
| record_format | Article |
| series | Autopsy and Case Reports |
| spelling | doaj.art-372510a49e774919aa2aee45f69f51a22024-02-26T16:08:01ZengUniversity of São PauloAutopsy and Case Reports2236-19602024-02-0114Exploring the unusual: a testosterone-secreting ovarian tumorHarpreet Kaur0Neha Singh1Sushma Bharti2Gurwinder Kaur3All India Institute of Medical Sciences (AIIMS), Department of Obstetrics and Gynecology, Bilaspur, Himachal Pradesh, India All India Institute of Medical Sciences (AIIMS), Department of Obstetrics and Gynecology, Bilaspur, Himachal Pradesh, India All India Institute of Medical Sciences (AIIMS), Department of Pathology, Bilaspur, Himachal Pradesh, IndiaAll India Institute of Medical Sciences (AIIMS), Department of Pathology, Bilaspur, Himachal Pradesh, India Ovarian steroid cell tumors are rare, representing less than 0.1% of all ovarian neoplasms. Among the myriad causes of hirsutism, ovarian tumors account for 1% of the reported cases. We present the case of a 49-year-old parous postmenopausal woman who sought medical attention for hirsutism for 2 years. This case illustrates the unusual and interesting connection between rare ovarian pathology and the clinical manifestation of hirsutism in a postmenopausal patient. Her ultrasonography and MRI showed a right adnexal mass of solid-cystic consistency with thin septations. Her laboratory workup revealed high levels of total testosterone of 256 ng/ml (8.4-48.1ng/ml) and free testosterone of 7.36 pg/ml (0.2-4.1 pg/ml), while DHEAS - 234 µg/dl (35.4-256 µg/dl) and CA125 - 15.8U/L (0.0-35 U/L) were in the normal range. She underwent exploratory laparotomy with a total abdominal hysterectomy and oophorectomy. Histopathological examination and immunohistochemistry conclusively established the presence of a steroid cell tumor, specifically classified as "Not Otherwise Specified"(NOS), in the right ovary. https://www.revistas.usp.br/autopsy/article/view/222442Ovarian neoplasmSex Cord-Gonadal Stromal TumoursHirsutismPostmenopause |
| spellingShingle | Harpreet Kaur Neha Singh Sushma Bharti Gurwinder Kaur Exploring the unusual: a testosterone-secreting ovarian tumor Autopsy and Case Reports Ovarian neoplasm Sex Cord-Gonadal Stromal Tumours Hirsutism Postmenopause |
| title | Exploring the unusual: a testosterone-secreting ovarian tumor |
| title_full | Exploring the unusual: a testosterone-secreting ovarian tumor |
| title_fullStr | Exploring the unusual: a testosterone-secreting ovarian tumor |
| title_full_unstemmed | Exploring the unusual: a testosterone-secreting ovarian tumor |
| title_short | Exploring the unusual: a testosterone-secreting ovarian tumor |
| title_sort | exploring the unusual a testosterone secreting ovarian tumor |
| topic | Ovarian neoplasm Sex Cord-Gonadal Stromal Tumours Hirsutism Postmenopause |
| url | https://www.revistas.usp.br/autopsy/article/view/222442 |
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