Controlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis

Controlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis

Hydrogen has been used to suppress tumor growth with considerable efficacy. Inhalation of hydrogen gas and oral ingestion of hydrogen-rich saline are two common systemic routes of hydrogen administration. We have developed a topical delivery method of hydrogen at targeted sites through the degradati...

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Bibliographic Details
Main Authors: Rui Zan, Hao Wang, Weijie Cai, Jiahua Ni, Bérengère J.C. Luthringer-Feyerabend, Wenhui Wang, Hongzhou Peng, Weiping Ji, Jun Yan, Jiazeng Xia, Yang Song, Xiaonong Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-03-01
Series:Bioactive Materials
Subjects:
Biodegradable magnesium
Hydrogen
Tumor apoptosis
Underlying mechanism
P53
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21003601

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