Pharmaco-economics: Minute-based cost of sevoflurane in pediatric short procedures and its relation to demographic variables

Background: Inhalation agents account for significant cost of short daycare procedures. The estimation of this cost to pre-calculate expected expenditure is not available in literature. As for intravenous agents, their relations to weight and other demographic parameters are also not well establishe...

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Main Authors: Preet Mohinder Singh, Anjan Trikha, Renu Sinha, Rashmi Ramachandran, Vimi Rewari, Anuradha Borle
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Journal of Anaesthesiology Clinical Pharmacology
Subjects:
Online Access:http://www.joacp.org/article.asp?issn=0970-9185;year=2013;volume=29;issue=3;spage=328;epage=332;aulast=Singh
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author Preet Mohinder Singh
Anjan Trikha
Renu Sinha
Rashmi Ramachandran
Vimi Rewari
Anuradha Borle
author_facet Preet Mohinder Singh
Anjan Trikha
Renu Sinha
Rashmi Ramachandran
Vimi Rewari
Anuradha Borle
author_sort Preet Mohinder Singh
collection DOAJ
description Background: Inhalation agents account for significant cost of short daycare procedures. The estimation of this cost to pre-calculate expected expenditure is not available in literature. As for intravenous agents, their relations to weight and other demographic parameters are also not well established. The present study aims to evaluate the above concern. Materials and Methods: A total of 100 pediatric (ASA I, II) patients scheduled for ophthalmological examination under anesthesia (EUA) were included in the study. Following premedication, anesthesia in all children was induced using incremental concentrations of sevoflurane at a flow of 6 l with 1:1 oxygen:nitrous oxide ratio. Upon induction, the flows were reduced to 2 l, keeping sevoflurane at 1 to 2 minimum alveolar concentration (MAC). Using Dion′s equation, the costs for induction and maintenance with sevoflurane were calculated for each patient. Results: The cost per minute of sevoflurane was found to be Rs. 13.23. Unlike intravenous agents, no significant correlation was found to exist between sevoflurane consumption with age or weight. The sevoflurane consumption was also not influenced by the gender. The total cost of EUA correlated most strongly with duration of maintenance phase, followed by induction duration.
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spelling doaj.art-372ad180ebd346b18a6c5abf94c8d51f2022-12-21T19:27:57ZengWolters Kluwer Medknow PublicationsJournal of Anaesthesiology Clinical Pharmacology0970-91852013-01-0129332833210.4103/0970-9185.117083Pharmaco-economics: Minute-based cost of sevoflurane in pediatric short procedures and its relation to demographic variablesPreet Mohinder SinghAnjan TrikhaRenu SinhaRashmi RamachandranVimi RewariAnuradha BorleBackground: Inhalation agents account for significant cost of short daycare procedures. The estimation of this cost to pre-calculate expected expenditure is not available in literature. As for intravenous agents, their relations to weight and other demographic parameters are also not well established. The present study aims to evaluate the above concern. Materials and Methods: A total of 100 pediatric (ASA I, II) patients scheduled for ophthalmological examination under anesthesia (EUA) were included in the study. Following premedication, anesthesia in all children was induced using incremental concentrations of sevoflurane at a flow of 6 l with 1:1 oxygen:nitrous oxide ratio. Upon induction, the flows were reduced to 2 l, keeping sevoflurane at 1 to 2 minimum alveolar concentration (MAC). Using Dion′s equation, the costs for induction and maintenance with sevoflurane were calculated for each patient. Results: The cost per minute of sevoflurane was found to be Rs. 13.23. Unlike intravenous agents, no significant correlation was found to exist between sevoflurane consumption with age or weight. The sevoflurane consumption was also not influenced by the gender. The total cost of EUA correlated most strongly with duration of maintenance phase, followed by induction duration.http://www.joacp.org/article.asp?issn=0970-9185;year=2013;volume=29;issue=3;spage=328;epage=332;aulast=SinghExamination under anesthesiapharmaco-economics in anesthesiasevoflurane cost
spellingShingle Preet Mohinder Singh
Anjan Trikha
Renu Sinha
Rashmi Ramachandran
Vimi Rewari
Anuradha Borle
Pharmaco-economics: Minute-based cost of sevoflurane in pediatric short procedures and its relation to demographic variables
Journal of Anaesthesiology Clinical Pharmacology
Examination under anesthesia
pharmaco-economics in anesthesia
sevoflurane cost
title Pharmaco-economics: Minute-based cost of sevoflurane in pediatric short procedures and its relation to demographic variables
title_full Pharmaco-economics: Minute-based cost of sevoflurane in pediatric short procedures and its relation to demographic variables
title_fullStr Pharmaco-economics: Minute-based cost of sevoflurane in pediatric short procedures and its relation to demographic variables
title_full_unstemmed Pharmaco-economics: Minute-based cost of sevoflurane in pediatric short procedures and its relation to demographic variables
title_short Pharmaco-economics: Minute-based cost of sevoflurane in pediatric short procedures and its relation to demographic variables
title_sort pharmaco economics minute based cost of sevoflurane in pediatric short procedures and its relation to demographic variables
topic Examination under anesthesia
pharmaco-economics in anesthesia
sevoflurane cost
url http://www.joacp.org/article.asp?issn=0970-9185;year=2013;volume=29;issue=3;spage=328;epage=332;aulast=Singh
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