Global epidemiology of prediabetes - present and future perspectives

Abstract Prediabetes is defined as an intermediate state of hyperglycaemia with glucose levels above the normal state but below the diagnostic levels of diabetes. It is increasingly recognised as an important metabolic state, as individuals with prediabetes are at high risk of developing overt diabe...

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Main Author: Ulrike Hostalek
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Clinical Diabetes and Endocrinology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40842-019-0080-0
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author Ulrike Hostalek
author_facet Ulrike Hostalek
author_sort Ulrike Hostalek
collection DOAJ
description Abstract Prediabetes is defined as an intermediate state of hyperglycaemia with glucose levels above the normal state but below the diagnostic levels of diabetes. It is increasingly recognised as an important metabolic state, as individuals with prediabetes are at high risk of developing overt diabetes and its associated complications. A better understanding of prediabetes could help with earlier identification, thereby allowing earlier intervention, potentially lowering the number of individuals who go on to develop diabetes. The definitions and screening criteria for prediabetes differ between guidelines published by different organisations, resulting in estimations of prevalence that can vary widely from one another. Despite these differences, these estimates suggest that the number of individuals affected by prediabetes is increasing rapidly in all areas of the world. This short review compares and contrasts the diagnostic criteria for screening of prediabetes, the impact of various glycaemic measures on prevalence estimates, and discusses current and future trends in the global prevalence estimates of prediabetes.
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spelling doaj.art-372ad956c0244f96a472dbd14f82f2222022-12-22T01:04:57ZengBMCClinical Diabetes and Endocrinology2055-82602019-05-01511510.1186/s40842-019-0080-0Global epidemiology of prediabetes - present and future perspectivesUlrike Hostalek0Global Medical Affairs, Merck KGaAAbstract Prediabetes is defined as an intermediate state of hyperglycaemia with glucose levels above the normal state but below the diagnostic levels of diabetes. It is increasingly recognised as an important metabolic state, as individuals with prediabetes are at high risk of developing overt diabetes and its associated complications. A better understanding of prediabetes could help with earlier identification, thereby allowing earlier intervention, potentially lowering the number of individuals who go on to develop diabetes. The definitions and screening criteria for prediabetes differ between guidelines published by different organisations, resulting in estimations of prevalence that can vary widely from one another. Despite these differences, these estimates suggest that the number of individuals affected by prediabetes is increasing rapidly in all areas of the world. This short review compares and contrasts the diagnostic criteria for screening of prediabetes, the impact of various glycaemic measures on prevalence estimates, and discusses current and future trends in the global prevalence estimates of prediabetes.http://link.springer.com/article/10.1186/s40842-019-0080-0PrediabetesDiabetesGlobal burdenPrevalenceScreening tools
spellingShingle Ulrike Hostalek
Global epidemiology of prediabetes - present and future perspectives
Clinical Diabetes and Endocrinology
Prediabetes
Diabetes
Global burden
Prevalence
Screening tools
title Global epidemiology of prediabetes - present and future perspectives
title_full Global epidemiology of prediabetes - present and future perspectives
title_fullStr Global epidemiology of prediabetes - present and future perspectives
title_full_unstemmed Global epidemiology of prediabetes - present and future perspectives
title_short Global epidemiology of prediabetes - present and future perspectives
title_sort global epidemiology of prediabetes present and future perspectives
topic Prediabetes
Diabetes
Global burden
Prevalence
Screening tools
url http://link.springer.com/article/10.1186/s40842-019-0080-0
work_keys_str_mv AT ulrikehostalek globalepidemiologyofprediabetespresentandfutureperspectives