There is no evidence that the addition of antimicrobials reduce the risk of sepsis after intra-articular corticosteroids in horses with arthritis
PICO question In horses with arthritis, does the treatment with intra-articular antimicrobials concurrently with intra-articular corticosteroids reduce the risk of sepsis compared to intra-articular corticosteroids alone? Clinical bottom line The three studies identified did not demonstrate...
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| Format: | Article |
| Language: | English |
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RCVS Knowledge
2020-01-01
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| Series: | Veterinary Evidence |
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| Online Access: | https://veterinaryevidence.org/index.php/ve/article/view/220 |
| _version_ | 1818533106903154688 |
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| author | Elena Gogua |
| author_facet | Elena Gogua |
| author_sort | Elena Gogua |
| collection | DOAJ |
| description | PICO question
In horses with arthritis, does the treatment with intra-articular antimicrobials concurrently with intra-articular corticosteroids reduce the risk of sepsis compared to intra-articular corticosteroids alone?
Clinical bottom line
The three studies identified did not demonstrate a reduction of risk when antimicrobials were used. However, the strength of evidence provided by the studies was weak. The power of the studies to detect an effect of antimicrobials was low due to the small number of sepsis cases recorded. Further studies are therefore required to draw conclusions. |
| first_indexed | 2024-12-11T17:54:18Z |
| format | Article |
| id | doaj.art-372d8ab28e424730986a5ca874b7f1d7 |
| institution | Directory Open Access Journal |
| issn | 2396-9776 |
| language | English |
| last_indexed | 2024-12-11T17:54:18Z |
| publishDate | 2020-01-01 |
| publisher | RCVS Knowledge |
| record_format | Article |
| series | Veterinary Evidence |
| spelling | doaj.art-372d8ab28e424730986a5ca874b7f1d72022-12-22T00:56:06ZengRCVS KnowledgeVeterinary Evidence2396-97762020-01-015110.18849/ve.v5i1.220220There is no evidence that the addition of antimicrobials reduce the risk of sepsis after intra-articular corticosteroids in horses with arthritisElena Gogua0Moscow state academy of veterinary medicine and biotechnology named K.I. Skryabin Academic Skryabin St., 23 Moscow, 109472PICO question In horses with arthritis, does the treatment with intra-articular antimicrobials concurrently with intra-articular corticosteroids reduce the risk of sepsis compared to intra-articular corticosteroids alone? Clinical bottom line The three studies identified did not demonstrate a reduction of risk when antimicrobials were used. However, the strength of evidence provided by the studies was weak. The power of the studies to detect an effect of antimicrobials was low due to the small number of sepsis cases recorded. Further studies are therefore required to draw conclusions.https://veterinaryevidence.org/index.php/ve/article/view/220equinearthritiscorticosteroidintra-articularantimicrobials |
| spellingShingle | Elena Gogua There is no evidence that the addition of antimicrobials reduce the risk of sepsis after intra-articular corticosteroids in horses with arthritis Veterinary Evidence equine arthritis corticosteroid intra-articular antimicrobials |
| title | There is no evidence that the addition of antimicrobials reduce the risk of sepsis after intra-articular corticosteroids in horses with arthritis |
| title_full | There is no evidence that the addition of antimicrobials reduce the risk of sepsis after intra-articular corticosteroids in horses with arthritis |
| title_fullStr | There is no evidence that the addition of antimicrobials reduce the risk of sepsis after intra-articular corticosteroids in horses with arthritis |
| title_full_unstemmed | There is no evidence that the addition of antimicrobials reduce the risk of sepsis after intra-articular corticosteroids in horses with arthritis |
| title_short | There is no evidence that the addition of antimicrobials reduce the risk of sepsis after intra-articular corticosteroids in horses with arthritis |
| title_sort | there is no evidence that the addition of antimicrobials reduce the risk of sepsis after intra articular corticosteroids in horses with arthritis |
| topic | equine arthritis corticosteroid intra-articular antimicrobials |
| url | https://veterinaryevidence.org/index.php/ve/article/view/220 |
| work_keys_str_mv | AT elenagogua thereisnoevidencethattheadditionofantimicrobialsreducetheriskofsepsisafterintraarticularcorticosteroidsinhorseswitharthritis |