S100A4 Is a Strong Negative Prognostic Marker and Potential Therapeutic Target in Adenocarcinoma of the Stomach and Esophagus

S100A4 Is a Strong Negative Prognostic Marker and Potential Therapeutic Target in Adenocarcinoma of the Stomach and Esophagus

Deregulated Wnt-signaling is a key mechanism driving metastasis in adenocarcinoma of the gastroesophageal junction and stomach (AGE/S). The oncogene <i>S100A4</i> was identified as a Wnt-signaling target gene and is known to promote metastasis. In this project, we illuminate the role of...

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Bibliographic Details
Main Authors: Christoph Treese, Kimberly Hartl, Michelle Pötzsch, Matthias Dahlmann, Moritz von Winterfeld, Erika Berg, Michael Hummel, Lena Timm, Beate Rau, Wolfgang Walther, Severin Daum, Dennis Kobelt, Ulrike Stein
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
gastric cancer
esophageal cancer
metastasis
S100A4
niclosamide
Online Access:https://www.mdpi.com/2073-4409/11/6/1056

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