Cardiac arrest caused by intramyometrial injection of vasopressin during a robotic-assisted laparoscopic myomectomy

Vasopressin is a locally-injected vasoconstrictor used to reduce bleeding during gynaecological surgery. However, even in these cases, vasopressin can induce adverse effects, including bradycardia, myocardial infarction and cardiac arrest. Elevated blood concentrations of vasopressin may induce the...

Full description

Bibliographic Details
Main Authors: Gang Geun Lee, Seung Youp Baek, Tae Woo Kim, Chang Young Jeong, Keon Hee Ryu, Dong Ho Park
Format: Article
Language:English
Published: SAGE Publishing 2018-12-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/0300060518805596
_version_ 1818723582734237696
author Gang Geun Lee
Seung Youp Baek
Tae Woo Kim
Chang Young Jeong
Keon Hee Ryu
Dong Ho Park
author_facet Gang Geun Lee
Seung Youp Baek
Tae Woo Kim
Chang Young Jeong
Keon Hee Ryu
Dong Ho Park
author_sort Gang Geun Lee
collection DOAJ
description Vasopressin is a locally-injected vasoconstrictor used to reduce bleeding during gynaecological surgery. However, even in these cases, vasopressin can induce adverse effects, including bradycardia, myocardial infarction and cardiac arrest. Elevated blood concentrations of vasopressin may induce the sympathoinhibitory reflex by increasing blood pressure and augment the sympathoinhibitory reflex by activating the area postrema. In addition, pneumoperitoneum formation needed for laparoscopy as well as physiological changes caused by steep Trendelenburg positions used during robotic surgeries may cause bradycardia. Shoulder braces used to prevent slipping from a steep Trendelenburg position may also be hazardous. This case report describes a 31-year-old female patient who underwent a scheduled robotic-assisted laparoscopic myomectomy in a steep Trendelenburg position. The patient experienced a cardiac arrest 2 min after the vasopressin injection and was treated accordingly. There were no abnormal findings on the postoperative laboratory studies, chest X-ray and electrocardiogram. The patient also had clear consciousness with no other notable symptoms. The patient was discharged on postoperative day 2. The report discusses the potential adverse effects of local vasopressin injection during robotic-assisted laparoscopic myomectomy.
first_indexed 2024-12-17T21:12:49Z
format Article
id doaj.art-372e9b8d78064f5b81c33232beb3f39e
institution Directory Open Access Journal
issn 0300-0605
1473-2300
language English
last_indexed 2024-12-17T21:12:49Z
publishDate 2018-12-01
publisher SAGE Publishing
record_format Article
series Journal of International Medical Research
spelling doaj.art-372e9b8d78064f5b81c33232beb3f39e2022-12-21T21:32:24ZengSAGE PublishingJournal of International Medical Research0300-06051473-23002018-12-014610.1177/0300060518805596Cardiac arrest caused by intramyometrial injection of vasopressin during a robotic-assisted laparoscopic myomectomyGang Geun LeeSeung Youp BaekTae Woo KimChang Young JeongKeon Hee RyuDong Ho ParkVasopressin is a locally-injected vasoconstrictor used to reduce bleeding during gynaecological surgery. However, even in these cases, vasopressin can induce adverse effects, including bradycardia, myocardial infarction and cardiac arrest. Elevated blood concentrations of vasopressin may induce the sympathoinhibitory reflex by increasing blood pressure and augment the sympathoinhibitory reflex by activating the area postrema. In addition, pneumoperitoneum formation needed for laparoscopy as well as physiological changes caused by steep Trendelenburg positions used during robotic surgeries may cause bradycardia. Shoulder braces used to prevent slipping from a steep Trendelenburg position may also be hazardous. This case report describes a 31-year-old female patient who underwent a scheduled robotic-assisted laparoscopic myomectomy in a steep Trendelenburg position. The patient experienced a cardiac arrest 2 min after the vasopressin injection and was treated accordingly. There were no abnormal findings on the postoperative laboratory studies, chest X-ray and electrocardiogram. The patient also had clear consciousness with no other notable symptoms. The patient was discharged on postoperative day 2. The report discusses the potential adverse effects of local vasopressin injection during robotic-assisted laparoscopic myomectomy.https://doi.org/10.1177/0300060518805596
spellingShingle Gang Geun Lee
Seung Youp Baek
Tae Woo Kim
Chang Young Jeong
Keon Hee Ryu
Dong Ho Park
Cardiac arrest caused by intramyometrial injection of vasopressin during a robotic-assisted laparoscopic myomectomy
Journal of International Medical Research
title Cardiac arrest caused by intramyometrial injection of vasopressin during a robotic-assisted laparoscopic myomectomy
title_full Cardiac arrest caused by intramyometrial injection of vasopressin during a robotic-assisted laparoscopic myomectomy
title_fullStr Cardiac arrest caused by intramyometrial injection of vasopressin during a robotic-assisted laparoscopic myomectomy
title_full_unstemmed Cardiac arrest caused by intramyometrial injection of vasopressin during a robotic-assisted laparoscopic myomectomy
title_short Cardiac arrest caused by intramyometrial injection of vasopressin during a robotic-assisted laparoscopic myomectomy
title_sort cardiac arrest caused by intramyometrial injection of vasopressin during a robotic assisted laparoscopic myomectomy
url https://doi.org/10.1177/0300060518805596
work_keys_str_mv AT ganggeunlee cardiacarrestcausedbyintramyometrialinjectionofvasopressinduringaroboticassistedlaparoscopicmyomectomy
AT seungyoupbaek cardiacarrestcausedbyintramyometrialinjectionofvasopressinduringaroboticassistedlaparoscopicmyomectomy
AT taewookim cardiacarrestcausedbyintramyometrialinjectionofvasopressinduringaroboticassistedlaparoscopicmyomectomy
AT changyoungjeong cardiacarrestcausedbyintramyometrialinjectionofvasopressinduringaroboticassistedlaparoscopicmyomectomy
AT keonheeryu cardiacarrestcausedbyintramyometrialinjectionofvasopressinduringaroboticassistedlaparoscopicmyomectomy
AT donghopark cardiacarrestcausedbyintramyometrialinjectionofvasopressinduringaroboticassistedlaparoscopicmyomectomy