Pharmaceutical care and medication adherence in management of psychosis in a Nigerian tertiary hospital
Objective: The primary objective of this study is to examine the medication adherence levels (as a function of pharmaceutical care) and its contributing factors in schizophrenic patients receiving antipsychotic drugs. Methods: This was a cross-sectional study administering a structured questionnair...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | Journal of Research in Pharmacy Practice |
| Subjects: | |
| Online Access: | http://www.jrpp.net/article.asp?issn=2319-9644;year=2013;volume=2;issue=2;spage=83;epage=87;aulast=Danladi |
| _version_ | 1819134713924681728 |
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| author | Jonathan Danladi Kakjing D Falang Raymond A Barde Nanlok S Jimam Dauda A Dangiwa Hafsat O Jimoh |
| author_facet | Jonathan Danladi Kakjing D Falang Raymond A Barde Nanlok S Jimam Dauda A Dangiwa Hafsat O Jimoh |
| author_sort | Jonathan Danladi |
| collection | DOAJ |
| description | Objective: The primary objective of this study is to examine the medication adherence levels (as a function of pharmaceutical care) and its contributing factors in schizophrenic patients receiving antipsychotic drugs.
Methods: This was a cross-sectional study administering a structured questionnaire to 231 patients. Adherence was measured through patient self-reporting. Association between independent variables and adherence to antipsychotics were measured through odds ratios (OR) in the univariate analysis while the best predictors of adherence were determined through the multiple logistic regressions.
Findings: Adherence level was found to be 65.8% (95% confidence interval [CI]: 59.3-71.9%). The following factors were identified to be associated with adherence in the univariate analysis: age (OR 1.088), sex (OR 1.231), employment (OR 0.366), marital status (singles, OR 0.022), drug adherence counseling (OR 11.641), twice a day frequency (OR 8.434), alcohol non-intake (OR 1.469), educational level (primary OR 1.9312, secondary OR 11.022, tertiary OR 4.771), occupation (public servant 6.273). In the multivariate analysis, age, three times a day frequency of drug intake, singles and educational levels such as primary, secondary or tertiary school, strongly affected adherence (P < 0.05).
Conclusion: Although patients adherence level was high (65.8%), there is a need to emphasize that pharmacists spend more time in counseling and educating patients, especially younger ones on drug adherence before any antipsychotic medications are dispensed. Furthermore, patients should be taught the use of adherence devices such as reminders so that adherence to antipsychotic medications can be optimized. |
| first_indexed | 2024-12-22T10:07:34Z |
| format | Article |
| id | doaj.art-372eb655e60a4b78bacf066be6fd72db |
| institution | Directory Open Access Journal |
| issn | 2319-9644 2279-042X |
| language | English |
| last_indexed | 2024-12-22T10:07:34Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Research in Pharmacy Practice |
| spelling | doaj.art-372eb655e60a4b78bacf066be6fd72db2022-12-21T18:29:55ZengWolters Kluwer Medknow PublicationsJournal of Research in Pharmacy Practice2319-96442279-042X2013-01-0122838710.4103/2279-042X.117388Pharmaceutical care and medication adherence in management of psychosis in a Nigerian tertiary hospitalJonathan DanladiKakjing D FalangRaymond A BardeNanlok S JimamDauda A DangiwaHafsat O JimohObjective: The primary objective of this study is to examine the medication adherence levels (as a function of pharmaceutical care) and its contributing factors in schizophrenic patients receiving antipsychotic drugs. Methods: This was a cross-sectional study administering a structured questionnaire to 231 patients. Adherence was measured through patient self-reporting. Association between independent variables and adherence to antipsychotics were measured through odds ratios (OR) in the univariate analysis while the best predictors of adherence were determined through the multiple logistic regressions. Findings: Adherence level was found to be 65.8% (95% confidence interval [CI]: 59.3-71.9%). The following factors were identified to be associated with adherence in the univariate analysis: age (OR 1.088), sex (OR 1.231), employment (OR 0.366), marital status (singles, OR 0.022), drug adherence counseling (OR 11.641), twice a day frequency (OR 8.434), alcohol non-intake (OR 1.469), educational level (primary OR 1.9312, secondary OR 11.022, tertiary OR 4.771), occupation (public servant 6.273). In the multivariate analysis, age, three times a day frequency of drug intake, singles and educational levels such as primary, secondary or tertiary school, strongly affected adherence (P < 0.05). Conclusion: Although patients adherence level was high (65.8%), there is a need to emphasize that pharmacists spend more time in counseling and educating patients, especially younger ones on drug adherence before any antipsychotic medications are dispensed. Furthermore, patients should be taught the use of adherence devices such as reminders so that adherence to antipsychotic medications can be optimized.http://www.jrpp.net/article.asp?issn=2319-9644;year=2013;volume=2;issue=2;spage=83;epage=87;aulast=DanladiAntipsychotic drugs; drug adherence; pharmaceutical care; schizophrenia |
| spellingShingle | Jonathan Danladi Kakjing D Falang Raymond A Barde Nanlok S Jimam Dauda A Dangiwa Hafsat O Jimoh Pharmaceutical care and medication adherence in management of psychosis in a Nigerian tertiary hospital Journal of Research in Pharmacy Practice Antipsychotic drugs; drug adherence; pharmaceutical care; schizophrenia |
| title | Pharmaceutical care and medication adherence in management of psychosis in a Nigerian tertiary hospital |
| title_full | Pharmaceutical care and medication adherence in management of psychosis in a Nigerian tertiary hospital |
| title_fullStr | Pharmaceutical care and medication adherence in management of psychosis in a Nigerian tertiary hospital |
| title_full_unstemmed | Pharmaceutical care and medication adherence in management of psychosis in a Nigerian tertiary hospital |
| title_short | Pharmaceutical care and medication adherence in management of psychosis in a Nigerian tertiary hospital |
| title_sort | pharmaceutical care and medication adherence in management of psychosis in a nigerian tertiary hospital |
| topic | Antipsychotic drugs; drug adherence; pharmaceutical care; schizophrenia |
| url | http://www.jrpp.net/article.asp?issn=2319-9644;year=2013;volume=2;issue=2;spage=83;epage=87;aulast=Danladi |
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