FLASH radiotherapy for the treatment of symptomatic bone metastases in the thorax (FAST-02): protocol for a prospective study of a novel radiotherapy approach

FLASH radiotherapy for the treatment of symptomatic bone metastases in the thorax (FAST-02): protocol for a prospective study of a novel radiotherapy approach

Abstract Background FLASH therapy is a treatment technique in which radiation is delivered at ultra-high dose rates (≥ 40 Gy/s). The first-in-human FAST-01 clinical trial demonstrated the clinical feasibility of proton FLASH in the treatment of extremity bone metastases. The objectives of this inves...

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Bibliographic Details
Main Authors: EC Daugherty, Y Zhang, Z Xiao, AE Mascia, M Sertorio, J Woo, C McCann, KJ Russell, RA Sharma, D Khuntia, JD Bradley, CB Simone, JC Breneman, JP Perentesis
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Radiation Oncology
Subjects:
FLASH radiotherapy
Proton therapy
Thoracic bone metastases
FLASH workflow
Safety
Efficacy
Online Access:https://doi.org/10.1186/s13014-024-02419-4

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