Invited review: Selective treatment of clinical mastitis in dairy cattle
ABSTRACT: Treatment of clinical mastitis (CM) and use of antimicrobials for dry cow therapy are responsible for the majority of animal-defined daily doses of antimicrobial use (AMU) on dairy farms. However, advancements made in the last decade have enabled excluding nonsevere CM cases from antimicro...
| Main Authors: | , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-06-01
|
| Series: | Journal of Dairy Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022030223001820 |
| _version_ | 1797818339727245312 |
|---|---|
| author | Ellen de Jong Kayley D. McCubbin David Speksnijder Simon Dufour John R. Middleton Pamela L. Ruegg Theo J.G.M. Lam David F. Kelton Scott McDougall Sandra M. Godden Alfonso Lago Päivi J. Rajala-Schultz Karin Orsel Sarne De Vliegher Volker Krömker Diego B. Nobrega John P. Kastelic Herman W. Barkema |
| author_facet | Ellen de Jong Kayley D. McCubbin David Speksnijder Simon Dufour John R. Middleton Pamela L. Ruegg Theo J.G.M. Lam David F. Kelton Scott McDougall Sandra M. Godden Alfonso Lago Päivi J. Rajala-Schultz Karin Orsel Sarne De Vliegher Volker Krömker Diego B. Nobrega John P. Kastelic Herman W. Barkema |
| author_sort | Ellen de Jong |
| collection | DOAJ |
| description | ABSTRACT: Treatment of clinical mastitis (CM) and use of antimicrobials for dry cow therapy are responsible for the majority of animal-defined daily doses of antimicrobial use (AMU) on dairy farms. However, advancements made in the last decade have enabled excluding nonsevere CM cases from antimicrobial treatment that have a high probability of cure without antimicrobials (no bacterial causes or gram-negative, excluding Klebsiella spp.) and cases with a low bacteriological cure rate (chronic cases). These advancements include availability of rapid diagnostic tests and improved udder health management practices, which reduced the incidence and infection pressure of contagious CM pathogens. This review informed an evidence-based protocol for selective CM treatment decisions based on a combination of rapid diagnostic test results, review of somatic cell count and CM records, and elucidated consequences in terms of udder health, AMU, and farm economics. Relatively fast identification of the causative agent is the most important factor in selective CM treatment protocols. Many reported studies did not indicate detrimental udder health consequences (e.g., reduced clinical or bacteriological cures, increased somatic cell count, increased culling rate, or increased recurrence of CM later in lactation) after initiating selective CM treatment protocols using on-farm testing. The magnitude of AMU reduction following a selective CM treatment protocol implementation depended on the causal pathogen distribution and protocol characteristics. Uptake of selective treatment of nonsevere CM cases differs across regions and is dependent on management systems and adoption of udder health programs. No economic losses or animal welfare issues are expected when adopting a selective versus blanket CM treatment protocol. Therefore, selective CM treatment of nonsevere cases can be a practical tool to aid AMU reduction on dairy farms. |
| first_indexed | 2024-03-13T09:06:38Z |
| format | Article |
| id | doaj.art-373150b14cd445b29e2ca53cb967c546 |
| institution | Directory Open Access Journal |
| issn | 0022-0302 |
| language | English |
| last_indexed | 2024-03-13T09:06:38Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Dairy Science |
| spelling | doaj.art-373150b14cd445b29e2ca53cb967c5462023-05-28T04:08:29ZengElsevierJournal of Dairy Science0022-03022023-06-01106637613778Invited review: Selective treatment of clinical mastitis in dairy cattleEllen de Jong0Kayley D. McCubbin1David Speksnijder2Simon Dufour3John R. Middleton4Pamela L. Ruegg5Theo J.G.M. Lam6David F. Kelton7Scott McDougall8Sandra M. Godden9Alfonso Lago10Päivi J. Rajala-Schultz11Karin Orsel12Sarne De Vliegher13Volker Krömker14Diego B. Nobrega15John P. Kastelic16Herman W. Barkema17Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada T2N 4N1; One Health at UCalgary, University of Calgary, AB, Canada T2N 4N1; Mastitis Network, Saint-Hyacinthe, QC, Canada J25 2M2Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada T2N 4N1; One Health at UCalgary, University of Calgary, AB, Canada T2N 4N1; Mastitis Network, Saint-Hyacinthe, QC, Canada J25 2M2Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, the Netherlands; University Animal Health Clinic ULP, 3481 LZ Harmelen, the NetherlandsMastitis Network, Saint-Hyacinthe, QC, Canada J25 2M2; Department of Pathology and Microbiology, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada J2S 2M2Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia 65211Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824Department Population Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, the Netherlands; GD Animal Health, 7400 AA Deventer, the NetherlandsMastitis Network, Saint-Hyacinthe, QC, Canada J25 2M2; Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada N1G 2W1Cognosco, Anexa, Morrinsville 3340, New Zealand; School of Veterinary Science, Massey University, Palmerston North 4442, New ZealandDepartment of Veterinary Population Medicine, University of Minnesota, St. Paul 55108DairyExperts Inc., Tulare, CA 93274Department of Production Animal Medicine, Faculty of Veterinary Medicine, 00014 University of Helsinki, FinlandFaculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada T2N 4N1M-team and Mastitis and Milk Quality Research Unit, Department of Internal Medicine, Reproduction and Population Health, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, BelgiumSection for Animal Production, Nutrition and Health, Department of Veterinary and Animal Sciences, University of Copenhagen, 1870 Frederiksberg, DenmarkFaculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada T2N 4N1; One Health at UCalgary, University of Calgary, AB, Canada T2N 4N1Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada T2N 4N1Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada T2N 4N1; One Health at UCalgary, University of Calgary, AB, Canada T2N 4N1; Mastitis Network, Saint-Hyacinthe, QC, Canada J25 2M2; Corresponding authorABSTRACT: Treatment of clinical mastitis (CM) and use of antimicrobials for dry cow therapy are responsible for the majority of animal-defined daily doses of antimicrobial use (AMU) on dairy farms. However, advancements made in the last decade have enabled excluding nonsevere CM cases from antimicrobial treatment that have a high probability of cure without antimicrobials (no bacterial causes or gram-negative, excluding Klebsiella spp.) and cases with a low bacteriological cure rate (chronic cases). These advancements include availability of rapid diagnostic tests and improved udder health management practices, which reduced the incidence and infection pressure of contagious CM pathogens. This review informed an evidence-based protocol for selective CM treatment decisions based on a combination of rapid diagnostic test results, review of somatic cell count and CM records, and elucidated consequences in terms of udder health, AMU, and farm economics. Relatively fast identification of the causative agent is the most important factor in selective CM treatment protocols. Many reported studies did not indicate detrimental udder health consequences (e.g., reduced clinical or bacteriological cures, increased somatic cell count, increased culling rate, or increased recurrence of CM later in lactation) after initiating selective CM treatment protocols using on-farm testing. The magnitude of AMU reduction following a selective CM treatment protocol implementation depended on the causal pathogen distribution and protocol characteristics. Uptake of selective treatment of nonsevere CM cases differs across regions and is dependent on management systems and adoption of udder health programs. No economic losses or animal welfare issues are expected when adopting a selective versus blanket CM treatment protocol. Therefore, selective CM treatment of nonsevere cases can be a practical tool to aid AMU reduction on dairy farms.http://www.sciencedirect.com/science/article/pii/S0022030223001820antimicrobial usedairy cattleclinical mastitisselective treatmentrapid diagnostic tests |
| spellingShingle | Ellen de Jong Kayley D. McCubbin David Speksnijder Simon Dufour John R. Middleton Pamela L. Ruegg Theo J.G.M. Lam David F. Kelton Scott McDougall Sandra M. Godden Alfonso Lago Päivi J. Rajala-Schultz Karin Orsel Sarne De Vliegher Volker Krömker Diego B. Nobrega John P. Kastelic Herman W. Barkema Invited review: Selective treatment of clinical mastitis in dairy cattle Journal of Dairy Science antimicrobial use dairy cattle clinical mastitis selective treatment rapid diagnostic tests |
| title | Invited review: Selective treatment of clinical mastitis in dairy cattle |
| title_full | Invited review: Selective treatment of clinical mastitis in dairy cattle |
| title_fullStr | Invited review: Selective treatment of clinical mastitis in dairy cattle |
| title_full_unstemmed | Invited review: Selective treatment of clinical mastitis in dairy cattle |
| title_short | Invited review: Selective treatment of clinical mastitis in dairy cattle |
| title_sort | invited review selective treatment of clinical mastitis in dairy cattle |
| topic | antimicrobial use dairy cattle clinical mastitis selective treatment rapid diagnostic tests |
| url | http://www.sciencedirect.com/science/article/pii/S0022030223001820 |
| work_keys_str_mv | AT ellendejong invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT kayleydmccubbin invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT davidspeksnijder invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT simondufour invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT johnrmiddleton invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT pamelalruegg invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT theojgmlam invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT davidfkelton invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT scottmcdougall invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT sandramgodden invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT alfonsolago invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT paivijrajalaschultz invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT karinorsel invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT sarnedevliegher invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT volkerkromker invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT diegobnobrega invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT johnpkastelic invitedreviewselectivetreatmentofclinicalmastitisindairycattle AT hermanwbarkema invitedreviewselectivetreatmentofclinicalmastitisindairycattle |