Effectiveness of combined antyviral therapy in children with chronic hepatitis C
The paper presents the results of the research on effectiveness of combined antiviral therapy conducted with pegylated interferon alpha 2b of prolonged action (Peginterferon alpha 2b at a dose of 60 mcg/m2 per week) and Rebetol (Ribavirin at a dose of 15 mg/kg per day) in 26 children with chronic vi...
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Format: | Article |
Language: | Russian |
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Journal Infectology
2014-09-01
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Series: | Журнал инфектологии |
Subjects: | |
Online Access: | https://journal.niidi.ru/jofin/article/view/166 |
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author | G. P. Martynova I. A. Solovyova T. A. Zhukovskaya A. B. Belkina Ya. A. Bogvilene I. A. Kutishcheva S. V. Evreimova |
author_facet | G. P. Martynova I. A. Solovyova T. A. Zhukovskaya A. B. Belkina Ya. A. Bogvilene I. A. Kutishcheva S. V. Evreimova |
author_sort | G. P. Martynova |
collection | DOAJ |
description | The paper presents the results of the research on effectiveness of combined antiviral therapy conducted with pegylated interferon alpha 2b of prolonged action (Peginterferon alpha 2b at a dose of 60 mcg/m2 per week) and Rebetol (Ribavirin at a dose of 15 mg/kg per day) in 26 children with chronic viral hepatitis C aged from 3 to 17, who underwent regular medical check-ups in City Clinical Hospital № 20 named after I.S. Berzon in Krasnoyarsk. Evaluation of effectiveness of combined antiviral therapy revealed that patients with genotype 1 had an immediate virologic response in 78,5% of cases, 83,3% of patients with genotype 2, 3 had a stable virologic response. |
first_indexed | 2024-03-12T04:52:41Z |
format | Article |
id | doaj.art-37367877718f477cbb5b572ffb2cb46b |
institution | Directory Open Access Journal |
issn | 2072-6732 |
language | Russian |
last_indexed | 2025-03-14T08:36:48Z |
publishDate | 2014-09-01 |
publisher | Journal Infectology |
record_format | Article |
series | Журнал инфектологии |
spelling | doaj.art-37367877718f477cbb5b572ffb2cb46b2025-03-02T13:00:24ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-0152374210.22625/2072-6732-2013-5-2-37-42180Effectiveness of combined antyviral therapy in children with chronic hepatitis CG. P. Martynova0I. A. Solovyova1T. A. Zhukovskaya2A. B. Belkina3Ya. A. Bogvilene4I. A. Kutishcheva5S. V. Evreimova6Krasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetskiy, KrasnoyarskKrasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetskiy, KrasnoyarskCity Clinical Hospital № 20 named after I.S. Berzon, KrasnoyarskCity Children Clinical Hospital № 1, KrasnoyarskKrasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetskiy, KrasnoyarskKrasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetskiy, KrasnoyarskCity Children Clinical Hospital № 1, KrasnoyarskThe paper presents the results of the research on effectiveness of combined antiviral therapy conducted with pegylated interferon alpha 2b of prolonged action (Peginterferon alpha 2b at a dose of 60 mcg/m2 per week) and Rebetol (Ribavirin at a dose of 15 mg/kg per day) in 26 children with chronic viral hepatitis C aged from 3 to 17, who underwent regular medical check-ups in City Clinical Hospital № 20 named after I.S. Berzon in Krasnoyarsk. Evaluation of effectiveness of combined antiviral therapy revealed that patients with genotype 1 had an immediate virologic response in 78,5% of cases, 83,3% of patients with genotype 2, 3 had a stable virologic response.https://journal.niidi.ru/jofin/article/view/166childrenchronic viral hepatitis ctherapy |
spellingShingle | G. P. Martynova I. A. Solovyova T. A. Zhukovskaya A. B. Belkina Ya. A. Bogvilene I. A. Kutishcheva S. V. Evreimova Effectiveness of combined antyviral therapy in children with chronic hepatitis C Журнал инфектологии children chronic viral hepatitis c therapy |
title | Effectiveness of combined antyviral therapy in children with chronic hepatitis C |
title_full | Effectiveness of combined antyviral therapy in children with chronic hepatitis C |
title_fullStr | Effectiveness of combined antyviral therapy in children with chronic hepatitis C |
title_full_unstemmed | Effectiveness of combined antyviral therapy in children with chronic hepatitis C |
title_short | Effectiveness of combined antyviral therapy in children with chronic hepatitis C |
title_sort | effectiveness of combined antyviral therapy in children with chronic hepatitis c |
topic | children chronic viral hepatitis c therapy |
url | https://journal.niidi.ru/jofin/article/view/166 |
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