Effectiveness of combined antyviral therapy in children with chronic hepatitis C

The paper presents the results of the research on effectiveness of combined antiviral therapy conducted with pegylated interferon alpha 2b of prolonged action (Peginterferon alpha 2b at a dose of 60 mcg/m2 per week) and Rebetol (Ribavirin at a dose of 15 mg/kg per day) in 26 children with chronic vi...

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Main Authors: G. P. Martynova, I. A. Solovyova, T. A. Zhukovskaya, A. B. Belkina, Ya. A. Bogvilene, I. A. Kutishcheva, S. V. Evreimova
Format: Article
Language:Russian
Published: Journal Infectology 2014-09-01
Series:Журнал инфектологии
Subjects:
Online Access:https://journal.niidi.ru/jofin/article/view/166
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author G. P. Martynova
I. A. Solovyova
T. A. Zhukovskaya
A. B. Belkina
Ya. A. Bogvilene
I. A. Kutishcheva
S. V. Evreimova
author_facet G. P. Martynova
I. A. Solovyova
T. A. Zhukovskaya
A. B. Belkina
Ya. A. Bogvilene
I. A. Kutishcheva
S. V. Evreimova
author_sort G. P. Martynova
collection DOAJ
description The paper presents the results of the research on effectiveness of combined antiviral therapy conducted with pegylated interferon alpha 2b of prolonged action (Peginterferon alpha 2b at a dose of 60 mcg/m2 per week) and Rebetol (Ribavirin at a dose of 15 mg/kg per day) in 26 children with chronic viral hepatitis C aged from 3 to 17, who underwent regular medical check-ups in City Clinical Hospital № 20 named after I.S. Berzon in Krasnoyarsk. Evaluation of effectiveness of combined antiviral therapy revealed that patients with genotype 1 had an immediate virologic response in 78,5% of cases, 83,3% of patients with genotype 2, 3 had a stable virologic response.
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spelling doaj.art-37367877718f477cbb5b572ffb2cb46b2025-03-02T13:00:24ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-0152374210.22625/2072-6732-2013-5-2-37-42180Effectiveness of combined antyviral therapy in children with chronic hepatitis CG. P. Martynova0I. A. Solovyova1T. A. Zhukovskaya2A. B. Belkina3Ya. A. Bogvilene4I. A. Kutishcheva5S. V. Evreimova6Krasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetskiy, KrasnoyarskKrasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetskiy, KrasnoyarskCity Clinical Hospital № 20 named after I.S. Berzon, KrasnoyarskCity Children Clinical Hospital № 1, KrasnoyarskKrasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetskiy, KrasnoyarskKrasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetskiy, KrasnoyarskCity Children Clinical Hospital № 1, KrasnoyarskThe paper presents the results of the research on effectiveness of combined antiviral therapy conducted with pegylated interferon alpha 2b of prolonged action (Peginterferon alpha 2b at a dose of 60 mcg/m2 per week) and Rebetol (Ribavirin at a dose of 15 mg/kg per day) in 26 children with chronic viral hepatitis C aged from 3 to 17, who underwent regular medical check-ups in City Clinical Hospital № 20 named after I.S. Berzon in Krasnoyarsk. Evaluation of effectiveness of combined antiviral therapy revealed that patients with genotype 1 had an immediate virologic response in 78,5% of cases, 83,3% of patients with genotype 2, 3 had a stable virologic response.https://journal.niidi.ru/jofin/article/view/166childrenchronic viral hepatitis ctherapy
spellingShingle G. P. Martynova
I. A. Solovyova
T. A. Zhukovskaya
A. B. Belkina
Ya. A. Bogvilene
I. A. Kutishcheva
S. V. Evreimova
Effectiveness of combined antyviral therapy in children with chronic hepatitis C
Журнал инфектологии
children
chronic viral hepatitis c
therapy
title Effectiveness of combined antyviral therapy in children with chronic hepatitis C
title_full Effectiveness of combined antyviral therapy in children with chronic hepatitis C
title_fullStr Effectiveness of combined antyviral therapy in children with chronic hepatitis C
title_full_unstemmed Effectiveness of combined antyviral therapy in children with chronic hepatitis C
title_short Effectiveness of combined antyviral therapy in children with chronic hepatitis C
title_sort effectiveness of combined antyviral therapy in children with chronic hepatitis c
topic children
chronic viral hepatitis c
therapy
url https://journal.niidi.ru/jofin/article/view/166
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