Extranodal natural killer/T-cell lymphoma with paraneoplastic eosinophilic myositis
Extranodal natural killer/T-cell lymphoma is a rare Epstein-Barr virus-associated aggressive lymphoma commonly involving the nasal and upper aerodigestive tract and, less commonly, extranodal sites such as skin and gastrointestinal tract. There is only one case report of paraneoplastic myositis asso...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-09-01
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| Series: | Human Pathology: Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214330020300407 |
| _version_ | 1818498490708262912 |
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| author | Jayati Mallick Jasmine Zain Dennis D. Weisenburger |
| author_facet | Jayati Mallick Jasmine Zain Dennis D. Weisenburger |
| author_sort | Jayati Mallick |
| collection | DOAJ |
| description | Extranodal natural killer/T-cell lymphoma is a rare Epstein-Barr virus-associated aggressive lymphoma commonly involving the nasal and upper aerodigestive tract and, less commonly, extranodal sites such as skin and gastrointestinal tract. There is only one case report of paraneoplastic myositis associated with this type of lymphoma. Here in we present a second case of paraneoplastic eosinophilic myositis seen in a patient with extranodal NK/T-cell lymphoma. Biopsy of one of the cutaneous nodules showed necrosis of the soft tissue and skeletal muscle with eosinophilic microabscess formation, along with peripheral blood eosinophilia. These nodules and the peripheral blood eosinophilia resolved with treatment of the cutaneous lymphoma. |
| first_indexed | 2024-12-10T20:15:53Z |
| format | Article |
| id | doaj.art-373754eded5342118daf3c9540c0aab4 |
| institution | Directory Open Access Journal |
| issn | 2214-3300 |
| language | English |
| last_indexed | 2024-12-10T20:15:53Z |
| publishDate | 2020-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Human Pathology: Case Reports |
| spelling | doaj.art-373754eded5342118daf3c9540c0aab42022-12-22T01:35:12ZengElsevierHuman Pathology: Case Reports2214-33002020-09-0121200391Extranodal natural killer/T-cell lymphoma with paraneoplastic eosinophilic myositisJayati Mallick0Jasmine Zain1Dennis D. Weisenburger2Department of Pathology, UT Southwestern Medical Center, City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA 91010, USA; Corresponding author at: Department of Pathology, 5939 Harry Hines Blvd, Dallas, TX 75390, USA.Department of Hematology, City of Hope National Medical Center, City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA 91010, USADepartment of Pathology, City of Hope National Medical Center, City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA 91010, USAExtranodal natural killer/T-cell lymphoma is a rare Epstein-Barr virus-associated aggressive lymphoma commonly involving the nasal and upper aerodigestive tract and, less commonly, extranodal sites such as skin and gastrointestinal tract. There is only one case report of paraneoplastic myositis associated with this type of lymphoma. Here in we present a second case of paraneoplastic eosinophilic myositis seen in a patient with extranodal NK/T-cell lymphoma. Biopsy of one of the cutaneous nodules showed necrosis of the soft tissue and skeletal muscle with eosinophilic microabscess formation, along with peripheral blood eosinophilia. These nodules and the peripheral blood eosinophilia resolved with treatment of the cutaneous lymphoma.http://www.sciencedirect.com/science/article/pii/S2214330020300407Extranodal natural killer/T-cell lymphomaParaneoplastic syndromeEosinophilic myositis |
| spellingShingle | Jayati Mallick Jasmine Zain Dennis D. Weisenburger Extranodal natural killer/T-cell lymphoma with paraneoplastic eosinophilic myositis Human Pathology: Case Reports Extranodal natural killer/T-cell lymphoma Paraneoplastic syndrome Eosinophilic myositis |
| title | Extranodal natural killer/T-cell lymphoma with paraneoplastic eosinophilic myositis |
| title_full | Extranodal natural killer/T-cell lymphoma with paraneoplastic eosinophilic myositis |
| title_fullStr | Extranodal natural killer/T-cell lymphoma with paraneoplastic eosinophilic myositis |
| title_full_unstemmed | Extranodal natural killer/T-cell lymphoma with paraneoplastic eosinophilic myositis |
| title_short | Extranodal natural killer/T-cell lymphoma with paraneoplastic eosinophilic myositis |
| title_sort | extranodal natural killer t cell lymphoma with paraneoplastic eosinophilic myositis |
| topic | Extranodal natural killer/T-cell lymphoma Paraneoplastic syndrome Eosinophilic myositis |
| url | http://www.sciencedirect.com/science/article/pii/S2214330020300407 |
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