Characterization of Secondary Metabolites Profile from Methanol Fraction of Temurui (Murraya koenigii (Linn.) Spreng) Leaves Using UPLC-MS
The leaves of the temurui (Murraya koenigii (Linn.) Spreng) plant has long been known and used by Indonesian and even Asian people as a traditional medicine to treat stomach aches and diabetes. This study aimed to determine the secondary metabolite profile of the methanol extract of M. koenigii lea...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya
2023-08-01
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| Series: | Borneo Journal of Pharmacy |
| Subjects: | |
| Online Access: | https://journal.umpr.ac.id/index.php/bjop/article/view/4662 |
| _version_ | 1827162119151288320 |
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| author | Intania Permata Adlis Santoni Afrizal Afrizal Trisno Afandi |
| author_facet | Intania Permata Adlis Santoni Afrizal Afrizal Trisno Afandi |
| author_sort | Intania Permata |
| collection | DOAJ |
| description |
The leaves of the temurui (Murraya koenigii (Linn.) Spreng) plant has long been known and used by Indonesian and even Asian people as a traditional medicine to treat stomach aches and diabetes. This study aimed to determine the secondary metabolite profile of the methanol extract of M. koenigii leaves. Murraya koenigii leaves fine powder was extracted in stages using n-hexane, ethyl acetate, and methanol. Each extract was prepared using a mixture of water, formic acid, acetonitrile, and formic acid, then injected into the UPLC-QTof-MS/MS tool, then analyzed with Masslynx and ChemSpider software. The results showed that the metabolite profile of the methanol extract of M. koenigii leaves contained 13 compounds, including phenolic, steroid, and alkaloid groups. Those compounds could be tested to identify their bioactivity.
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| first_indexed | 2024-03-12T11:55:32Z |
| format | Article |
| id | doaj.art-37379c41ce754f2c8b880707f027a925 |
| institution | Directory Open Access Journal |
| issn | 2621-4814 |
| language | English |
| last_indexed | 2025-03-21T00:39:44Z |
| publishDate | 2023-08-01 |
| publisher | Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya |
| record_format | Article |
| series | Borneo Journal of Pharmacy |
| spelling | doaj.art-37379c41ce754f2c8b880707f027a9252024-08-03T06:28:34ZengInstitute for Researches and Community Services Universitas Muhammadiyah PalangkarayaBorneo Journal of Pharmacy2621-48142023-08-016310.33084/bjop.v6i3.4662Characterization of Secondary Metabolites Profile from Methanol Fraction of Temurui (Murraya koenigii (Linn.) Spreng) Leaves Using UPLC-MSIntania Permata0Adlis Santoni1Afrizal Afrizal2Trisno Afandi3Politeknik ATI PadangUniversitas AndalasUniversitas AndalasPoliteknik Teknologi Kimia Industri Medan The leaves of the temurui (Murraya koenigii (Linn.) Spreng) plant has long been known and used by Indonesian and even Asian people as a traditional medicine to treat stomach aches and diabetes. This study aimed to determine the secondary metabolite profile of the methanol extract of M. koenigii leaves. Murraya koenigii leaves fine powder was extracted in stages using n-hexane, ethyl acetate, and methanol. Each extract was prepared using a mixture of water, formic acid, acetonitrile, and formic acid, then injected into the UPLC-QTof-MS/MS tool, then analyzed with Masslynx and ChemSpider software. The results showed that the metabolite profile of the methanol extract of M. koenigii leaves contained 13 compounds, including phenolic, steroid, and alkaloid groups. Those compounds could be tested to identify their bioactivity. https://journal.umpr.ac.id/index.php/bjop/article/view/4662UPLC-MSmasslynxMetabolite profilingMurraya koenigii |
| spellingShingle | Intania Permata Adlis Santoni Afrizal Afrizal Trisno Afandi Characterization of Secondary Metabolites Profile from Methanol Fraction of Temurui (Murraya koenigii (Linn.) Spreng) Leaves Using UPLC-MS Borneo Journal of Pharmacy UPLC-MS masslynx Metabolite profiling Murraya koenigii |
| title | Characterization of Secondary Metabolites Profile from Methanol Fraction of Temurui (Murraya koenigii (Linn.) Spreng) Leaves Using UPLC-MS |
| title_full | Characterization of Secondary Metabolites Profile from Methanol Fraction of Temurui (Murraya koenigii (Linn.) Spreng) Leaves Using UPLC-MS |
| title_fullStr | Characterization of Secondary Metabolites Profile from Methanol Fraction of Temurui (Murraya koenigii (Linn.) Spreng) Leaves Using UPLC-MS |
| title_full_unstemmed | Characterization of Secondary Metabolites Profile from Methanol Fraction of Temurui (Murraya koenigii (Linn.) Spreng) Leaves Using UPLC-MS |
| title_short | Characterization of Secondary Metabolites Profile from Methanol Fraction of Temurui (Murraya koenigii (Linn.) Spreng) Leaves Using UPLC-MS |
| title_sort | characterization of secondary metabolites profile from methanol fraction of temurui murraya koenigii linn spreng leaves using uplc ms |
| topic | UPLC-MS masslynx Metabolite profiling Murraya koenigii |
| url | https://journal.umpr.ac.id/index.php/bjop/article/view/4662 |
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