The SP1-12LOX axis promotes chemoresistance and metastasis of ovarian cancer

The SP1-12LOX axis promotes chemoresistance and metastasis of ovarian cancer

Abstract Background Ovarian cancer is the most lethal gynecologic cancer. Chemoresistance, especially platinum-resistance, is closely related to metastasis of ovarian cancer, however, the molecular basis by which links chemoresistance and metastasis remains vague. Disordered arachidonic acid (AA) me...

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Bibliographic Details
Main Authors: Qi Zhang, Guifang Yan, Juan Lei, Yu Chen, Ting Wang, Juan Gong, Yong Zhou, Huakan Zhao, Hao Chen, Yu Zhou, Lei Wu, Jiangang Zhang, Xiao Zhang, Jingchun Wang, Yongsheng Li
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Molecular Medicine
Subjects:
SP1
Lipoxygenase
Chemoresistance
Metastasis
Ovarian cancer
Online Access:http://link.springer.com/article/10.1186/s10020-020-00174-2

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