Some Aspects of Protozoan Infections in Immunocompromised Patients: A Review

Protozoa are among the most important pathogens that can cause infections in immunocompromised hosts. These microorganisms particularly infect individuals with impaired cellular immunity, such as those with hematological neoplasias, renal or heart transplant patients, patients using high doses of co...

Full description

Bibliographic Details
Main Authors: Ferreira Marcelo Simão, Borges Aércio Sebastião
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2002-01-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000400001
_version_ 1797704718526447616
author Ferreira Marcelo Simão
Borges Aércio Sebastião
author_facet Ferreira Marcelo Simão
Borges Aércio Sebastião
author_sort Ferreira Marcelo Simão
collection DOAJ
description Protozoa are among the most important pathogens that can cause infections in immunocompromised hosts. These microorganisms particularly infect individuals with impaired cellular immunity, such as those with hematological neoplasias, renal or heart transplant patients, patients using high doses of corticosteroids, and patients with acquired immunodeficiency syndrome. The protozoa that most frequently cause disease in immunocompromised patients are Toxoplasma gondii, Trypanosoma cruzi, different Leishmania species, and Cryptosporidium parvum; the first two species cause severe acute meningoencephalitis and acute myocarditis, Leishmania sp. causes mucocutaneous or visceral disease, and Cryptosporidium can lead to chronic diarrhea with hepatobiliary involvement. Various serological, parasitological, histological and molecular methods for the diagnosis of these infections are currently available and early institution of specific therapy for each of these organisms is a basic measure to reduce the morbidity and mortality associated with these infections.
first_indexed 2024-03-12T05:24:35Z
format Article
id doaj.art-3741d451ad2b4071a5d91e62d20d974c
institution Directory Open Access Journal
issn 0074-0276
1678-8060
language English
last_indexed 2024-03-12T05:24:35Z
publishDate 2002-01-01
publisher Fundação Oswaldo Cruz (FIOCRUZ)
record_format Article
series Memorias do Instituto Oswaldo Cruz
spelling doaj.art-3741d451ad2b4071a5d91e62d20d974c2023-09-03T07:25:01ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602002-01-01974443457Some Aspects of Protozoan Infections in Immunocompromised Patients: A ReviewFerreira Marcelo SimãoBorges Aércio SebastiãoProtozoa are among the most important pathogens that can cause infections in immunocompromised hosts. These microorganisms particularly infect individuals with impaired cellular immunity, such as those with hematological neoplasias, renal or heart transplant patients, patients using high doses of corticosteroids, and patients with acquired immunodeficiency syndrome. The protozoa that most frequently cause disease in immunocompromised patients are Toxoplasma gondii, Trypanosoma cruzi, different Leishmania species, and Cryptosporidium parvum; the first two species cause severe acute meningoencephalitis and acute myocarditis, Leishmania sp. causes mucocutaneous or visceral disease, and Cryptosporidium can lead to chronic diarrhea with hepatobiliary involvement. Various serological, parasitological, histological and molecular methods for the diagnosis of these infections are currently available and early institution of specific therapy for each of these organisms is a basic measure to reduce the morbidity and mortality associated with these infections.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000400001protozoaacquired immunodeficiency syndromeAidsopportunistic infections
spellingShingle Ferreira Marcelo Simão
Borges Aércio Sebastião
Some Aspects of Protozoan Infections in Immunocompromised Patients: A Review
Memorias do Instituto Oswaldo Cruz
protozoa
acquired immunodeficiency syndrome
Aids
opportunistic infections
title Some Aspects of Protozoan Infections in Immunocompromised Patients: A Review
title_full Some Aspects of Protozoan Infections in Immunocompromised Patients: A Review
title_fullStr Some Aspects of Protozoan Infections in Immunocompromised Patients: A Review
title_full_unstemmed Some Aspects of Protozoan Infections in Immunocompromised Patients: A Review
title_short Some Aspects of Protozoan Infections in Immunocompromised Patients: A Review
title_sort some aspects of protozoan infections in immunocompromised patients a review
topic protozoa
acquired immunodeficiency syndrome
Aids
opportunistic infections
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000400001
work_keys_str_mv AT ferreiramarcelosimao someaspectsofprotozoaninfectionsinimmunocompromisedpatientsareview
AT borgesaerciosebastiao someaspectsofprotozoaninfectionsinimmunocompromisedpatientsareview