Isolation, cultivation, and in vitro susceptibility testing of Borrelia burgdorferi sensu lato: A review
Lyme borreliosis is the most common vector-borne disease in the northern hemisphere. The agents of Lyme borreliosis are borrelia, bacteria of the family Spirochaetaceae, which are grouped in Borrelia burgdorferi sensu lato species complex. Borreliae are fastidious, slow-growing and biochemically...
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| Format: | Article |
| Language: | English |
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University of Belgrade, University of Novi Sad
2013-01-01
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| Series: | Archives of Biological Sciences |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0354-4664/2013/0354-46641302533V.pdf |
| _version_ | 1818928590379548672 |
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| author | Veinović Gorana Filipić Brankica Stanković Jelena |
| author_facet | Veinović Gorana Filipić Brankica Stanković Jelena |
| author_sort | Veinović Gorana |
| collection | DOAJ |
| description | Lyme borreliosis is the most common vector-borne disease in the northern hemisphere. The agents of Lyme borreliosis are borrelia, bacteria of the family Spirochaetaceae, which are grouped in Borrelia burgdorferi sensu lato species complex. Borreliae are fastidious, slow-growing and biochemically inactive bacteria that need special attention and optimal conditions for cultivation. The isolation of Borrelia from clinical material and their cultivation is a time-consuming and demanding procedure. Cultivation lasts from 9 up to 12 weeks, which is much longer than is necessary to grow most other human bacterial pathogens. Although B. burgdorferi sensu lato is susceptible to a wide range of antimicrobial agents in vitro, up to now the susceptibility of individual Borrelia species to antibiotics is defined only partially. [Projekat Ministarstva nauke Republike Srbije, br. 175011] |
| first_indexed | 2024-12-20T03:31:20Z |
| format | Article |
| id | doaj.art-3745abd873a54acda17f3b9362714d9b |
| institution | Directory Open Access Journal |
| issn | 0354-4664 1821-4339 |
| language | English |
| last_indexed | 2024-12-20T03:31:20Z |
| publishDate | 2013-01-01 |
| publisher | University of Belgrade, University of Novi Sad |
| record_format | Article |
| series | Archives of Biological Sciences |
| spelling | doaj.art-3745abd873a54acda17f3b9362714d9b2022-12-21T19:54:58ZengUniversity of Belgrade, University of Novi SadArchives of Biological Sciences0354-46641821-43392013-01-0165253354710.2298/ABS1302533VIsolation, cultivation, and in vitro susceptibility testing of Borrelia burgdorferi sensu lato: A reviewVeinović GoranaFilipić BrankicaStanković JelenaLyme borreliosis is the most common vector-borne disease in the northern hemisphere. The agents of Lyme borreliosis are borrelia, bacteria of the family Spirochaetaceae, which are grouped in Borrelia burgdorferi sensu lato species complex. Borreliae are fastidious, slow-growing and biochemically inactive bacteria that need special attention and optimal conditions for cultivation. The isolation of Borrelia from clinical material and their cultivation is a time-consuming and demanding procedure. Cultivation lasts from 9 up to 12 weeks, which is much longer than is necessary to grow most other human bacterial pathogens. Although B. burgdorferi sensu lato is susceptible to a wide range of antimicrobial agents in vitro, up to now the susceptibility of individual Borrelia species to antibiotics is defined only partially. [Projekat Ministarstva nauke Republike Srbije, br. 175011]http://www.doiserbia.nb.rs/img/doi/0354-4664/2013/0354-46641302533V.pdfBorreliagrowth conditions in vitrosusceptibility testing |
| spellingShingle | Veinović Gorana Filipić Brankica Stanković Jelena Isolation, cultivation, and in vitro susceptibility testing of Borrelia burgdorferi sensu lato: A review Archives of Biological Sciences Borrelia growth conditions in vitro susceptibility testing |
| title | Isolation, cultivation, and in vitro susceptibility testing of Borrelia burgdorferi sensu lato: A review |
| title_full | Isolation, cultivation, and in vitro susceptibility testing of Borrelia burgdorferi sensu lato: A review |
| title_fullStr | Isolation, cultivation, and in vitro susceptibility testing of Borrelia burgdorferi sensu lato: A review |
| title_full_unstemmed | Isolation, cultivation, and in vitro susceptibility testing of Borrelia burgdorferi sensu lato: A review |
| title_short | Isolation, cultivation, and in vitro susceptibility testing of Borrelia burgdorferi sensu lato: A review |
| title_sort | isolation cultivation and in vitro susceptibility testing of borrelia burgdorferi sensu lato a review |
| topic | Borrelia growth conditions in vitro susceptibility testing |
| url | http://www.doiserbia.nb.rs/img/doi/0354-4664/2013/0354-46641302533V.pdf |
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