RIG-I Plays a Dominant Role in the Induction of Transcriptional Changes in Zika Virus-Infected Cells, which Protect from Virus-Induced Cell Death

RIG-I Plays a Dominant Role in the Induction of Transcriptional Changes in Zika Virus-Infected Cells, which Protect from Virus-Induced Cell Death

The Zika virus (ZIKV) has received much attention due to an alarming increase in cases of neurological disorders including congenital Zika syndrome associated with infection. To date, there is no effective treatment available. An immediate response by the innate immune system is crucial for effectiv...

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Bibliographic Details
Main Authors: Mirjam Schilling, Anne Bridgeman, Nicki Gray, Jonny Hertzog, Philip Hublitz, Alain Kohl, Jan Rehwinkel
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
Zika virus
IFN
RIG-I
MDA5
apoptosis
NS5
Online Access:https://www.mdpi.com/2073-4409/9/6/1476

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