Impact of taxane-based chemotherapeutics on male reproductive function
Men and boys with cancer treated with chemotherapy are known to have reduced fertility following their treatment. This is because some chemotherapy drugs can damage the cells in the testicles that make sperm. This study found there is limited information available on the effect of one group of chemo...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Bioscientifica
2023-04-01
|
| Series: | Reproduction and Fertility |
| Subjects: | |
| Online Access: | https://raf.bioscientifica.com/view/journals/raf/4/1/RAF-22-0134.xml |
| _version_ | 1827973393294557184 |
|---|---|
| author | Charvi Kanodia Michael P Rimmer Kathleen Duffin Rod T Mitchell |
| author_facet | Charvi Kanodia Michael P Rimmer Kathleen Duffin Rod T Mitchell |
| author_sort | Charvi Kanodia |
| collection | DOAJ |
| description | Men and boys with cancer treated with chemotherapy are known to have reduced fertility following their treatment. This is because some chemotherapy drugs can damage the cells in the testicles that make sperm. This study found there is limited information available on the effect of one group of chemotherapy drugs, called taxanes, on testicular function and fertility. More studies are needed to aid clinicians in advising patients on how this taxane-based chemotherapy may affect their future fertility. |
| first_indexed | 2024-04-09T19:36:23Z |
| format | Article |
| id | doaj.art-3748eb4e90854293a4607323cdb46d9e |
| institution | Directory Open Access Journal |
| issn | 2633-8386 |
| language | English |
| last_indexed | 2024-04-09T19:36:23Z |
| publishDate | 2023-04-01 |
| publisher | Bioscientifica |
| record_format | Article |
| series | Reproduction and Fertility |
| spelling | doaj.art-3748eb4e90854293a4607323cdb46d9e2023-04-04T11:36:09ZengBioscientificaReproduction and Fertility2633-83862023-04-014114https://doi.org/10.1530/RAF-22-0134Impact of taxane-based chemotherapeutics on male reproductive functionCharvi Kanodia0Michael P Rimmer1Kathleen Duffin2Rod T Mitchell3Edinburgh Medical School, University of Edinburgh, UKMRC Centre for Reproductive Health, Institute of Regeneration and Repair, University of Edinburgh, UKBiomedical Sciences, University of Edinburgh, UKMRC Centre for Reproductive Health, Institute of Regeneration and Repair, University of Edinburgh, UKMen and boys with cancer treated with chemotherapy are known to have reduced fertility following their treatment. This is because some chemotherapy drugs can damage the cells in the testicles that make sperm. This study found there is limited information available on the effect of one group of chemotherapy drugs, called taxanes, on testicular function and fertility. More studies are needed to aid clinicians in advising patients on how this taxane-based chemotherapy may affect their future fertility.https://raf.bioscientifica.com/view/journals/raf/4/1/RAF-22-0134.xmlfertility preservationfertilitytaxaneschemotherapypaclitaxel |
| spellingShingle | Charvi Kanodia Michael P Rimmer Kathleen Duffin Rod T Mitchell Impact of taxane-based chemotherapeutics on male reproductive function Reproduction and Fertility fertility preservation fertility taxanes chemotherapy paclitaxel |
| title | Impact of taxane-based chemotherapeutics on male reproductive function |
| title_full | Impact of taxane-based chemotherapeutics on male reproductive function |
| title_fullStr | Impact of taxane-based chemotherapeutics on male reproductive function |
| title_full_unstemmed | Impact of taxane-based chemotherapeutics on male reproductive function |
| title_short | Impact of taxane-based chemotherapeutics on male reproductive function |
| title_sort | impact of taxane based chemotherapeutics on male reproductive function |
| topic | fertility preservation fertility taxanes chemotherapy paclitaxel |
| url | https://raf.bioscientifica.com/view/journals/raf/4/1/RAF-22-0134.xml |
| work_keys_str_mv | AT charvikanodia impactoftaxanebasedchemotherapeuticsonmalereproductivefunction AT michaelprimmer impactoftaxanebasedchemotherapeuticsonmalereproductivefunction AT kathleenduffin impactoftaxanebasedchemotherapeuticsonmalereproductivefunction AT rodtmitchell impactoftaxanebasedchemotherapeuticsonmalereproductivefunction |