Trace Element Selenium Effectively Alleviates Intestinal Diseases

Selenium (Se) is an essential trace element in the body. It is mainly used in the body in the form of selenoproteins and has a variety of biological functions. Intestinal diseases caused by chronic inflammation are among the most important threats to human health, and there is no complete cure at pr...

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Main Authors: Ruihua Ye, Jiaqiang Huang, Zixu Wang, Yaoxing Chen, Yulan Dong
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/21/11708
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author Ruihua Ye
Jiaqiang Huang
Zixu Wang
Yaoxing Chen
Yulan Dong
author_facet Ruihua Ye
Jiaqiang Huang
Zixu Wang
Yaoxing Chen
Yulan Dong
author_sort Ruihua Ye
collection DOAJ
description Selenium (Se) is an essential trace element in the body. It is mainly used in the body in the form of selenoproteins and has a variety of biological functions. Intestinal diseases caused by chronic inflammation are among the most important threats to human health, and there is no complete cure at present. Due to its excellent antioxidant function, Se has been proven to be effective in alleviating intestinal diseases such as inflammatory bowel diseases (IBDs). Therefore, this paper introduces the role of Se and selenoproteins in the intestinal tract and the mechanism of their involvement in the mediation of intestinal diseases. In addition, it introduces the advantages and disadvantages of nano-Se as a new Se preparation and traditional Se supplement in the prevention and treatment of intestinal diseases, so as to provide a reference for the further exploration of the interaction between selenium and intestinal health.
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spelling doaj.art-3749fdf512384e93a1f029d6c34a35d72023-11-22T20:56:36ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-10-0122211170810.3390/ijms222111708Trace Element Selenium Effectively Alleviates Intestinal DiseasesRuihua Ye0Jiaqiang Huang1Zixu Wang2Yaoxing Chen3Yulan Dong4College of Veterinary Medicine, China Agricultural University, Beijing 100193, ChinaKey Laboratory of Precision Nutrition and Food Quality, Ministry of Education, China Agricultural University, Beijing 100193, ChinaCollege of Veterinary Medicine, China Agricultural University, Beijing 100193, ChinaCollege of Veterinary Medicine, China Agricultural University, Beijing 100193, ChinaCollege of Veterinary Medicine, China Agricultural University, Beijing 100193, ChinaSelenium (Se) is an essential trace element in the body. It is mainly used in the body in the form of selenoproteins and has a variety of biological functions. Intestinal diseases caused by chronic inflammation are among the most important threats to human health, and there is no complete cure at present. Due to its excellent antioxidant function, Se has been proven to be effective in alleviating intestinal diseases such as inflammatory bowel diseases (IBDs). Therefore, this paper introduces the role of Se and selenoproteins in the intestinal tract and the mechanism of their involvement in the mediation of intestinal diseases. In addition, it introduces the advantages and disadvantages of nano-Se as a new Se preparation and traditional Se supplement in the prevention and treatment of intestinal diseases, so as to provide a reference for the further exploration of the interaction between selenium and intestinal health.https://www.mdpi.com/1422-0067/22/21/11708seleniumselenoproteinsintestinal diseasesIBDSeNPs
spellingShingle Ruihua Ye
Jiaqiang Huang
Zixu Wang
Yaoxing Chen
Yulan Dong
Trace Element Selenium Effectively Alleviates Intestinal Diseases
International Journal of Molecular Sciences
selenium
selenoproteins
intestinal diseases
IBD
SeNPs
title Trace Element Selenium Effectively Alleviates Intestinal Diseases
title_full Trace Element Selenium Effectively Alleviates Intestinal Diseases
title_fullStr Trace Element Selenium Effectively Alleviates Intestinal Diseases
title_full_unstemmed Trace Element Selenium Effectively Alleviates Intestinal Diseases
title_short Trace Element Selenium Effectively Alleviates Intestinal Diseases
title_sort trace element selenium effectively alleviates intestinal diseases
topic selenium
selenoproteins
intestinal diseases
IBD
SeNPs
url https://www.mdpi.com/1422-0067/22/21/11708
work_keys_str_mv AT ruihuaye traceelementseleniumeffectivelyalleviatesintestinaldiseases
AT jiaqianghuang traceelementseleniumeffectivelyalleviatesintestinaldiseases
AT zixuwang traceelementseleniumeffectivelyalleviatesintestinaldiseases
AT yaoxingchen traceelementseleniumeffectivelyalleviatesintestinaldiseases
AT yulandong traceelementseleniumeffectivelyalleviatesintestinaldiseases