Vilya, a component of the recombination nodule, is required for meiotic double-strand break formation in Drosophila

Vilya, a component of the recombination nodule, is required for meiotic double-strand break formation in Drosophila

Meiotic recombination begins with the induction of programmed double-strand breaks (DSBs). In most organisms only a fraction of DSBs become crossovers. Here we report a novel meiotic gene, vilya, which encodes a protein with homology to Zip3-like proteins shown to determine DSB fate in other organis...

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Bibliographic Details
Main Authors: Cathleen M Lake, Rachel J Nielsen, Fengli Guo, Jay R Unruh, Brian D Slaughter, R Scott Hawley
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-10-01
Series:eLife
Subjects:
meiosis
recombination
synaptonemal complex
double-strand break
recombination nodule
Online Access:https://elifesciences.org/articles/08287

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