The potential of mobile health applications to improve couples’ fertility: a systematic review and meta-analysis of randomized controlled trials
The purpose of this systematic review was to examine the safety and effectiveness of mobile health applications in couples with infertility. Nineteen databases were searched from their inception to August 2022. Only randomized controlled trials (RCTs) in which mobile health was used as an interve...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MRE Press
2023-03-01
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| Series: | Journal of Men's Health |
| Subjects: | |
| Online Access: | https://oss.jomh.org/files/article/20230330-65/pdf/JOMH15968.pdf |
| _version_ | 1797326569389162496 |
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| author | Ying Li Wan-jia Shen Xiao-lin Wu Xian-wen Jin |
| author_facet | Ying Li Wan-jia Shen Xiao-lin Wu Xian-wen Jin |
| author_sort | Ying Li |
| collection | DOAJ |
| description | The purpose of this systematic review was to examine the safety and
effectiveness of mobile health applications in couples with infertility. Nineteen
databases were searched from their inception to August 2022. Only randomized
controlled trials (RCTs) in which mobile health was used as an intervention in
infertile couples were included. A quantitative analysis of RCTs was employed
using RevMan software. Study selection, data extraction and validation were
performed by two independent reviewers according to the guidelines. The Cochrane
criteria for risk-of-bias were used to evaluate the methodological quality of the
trials. Eight RCTs met the inclusion criteria. Among the eight RCTs, two RCTs
were from the Netherlands and the remaining six RCTs were from China.
Meta-analysis showed that mobile health interventions in infertile couples in
China were found to be superior to usual care in terms of clinical pregnancy rate
(p = 0.001), psychological status (SAS (Self-Rating Anxiety Scale):
p < 0.001; SDS (Self-Rating Depression Scale) p < 0.001;),
infertility knowledge levels (p < 0.001), quality of life (p
< 0.001), and serum levels of 5-hydroxytryptamine (p < 0.001). The
effects on intervention groups using mobile health interventions in the
Netherlands were not superior to the control groups that used usual care in terms
of improving dietary factors (p > 0.05). In general, the positive
effect of mobile health on improving clinical pregnancy rate, psychological
status, infertility knowledge levels, quality of life and satisfaction with
information was better than that of usual care. Mobile health interventions could
be a viable supplement to the usual care for infertile couples. However, more
high-quality RCTs need to be included in the future to provide additional
evidence of the positive effects of mobile health in infertile couples. |
| first_indexed | 2024-03-08T06:26:07Z |
| format | Article |
| id | doaj.art-374b73f778754d04a88578224bcfaa2a |
| institution | Directory Open Access Journal |
| issn | 1875-6859 |
| language | English |
| last_indexed | 2024-03-08T06:26:07Z |
| publishDate | 2023-03-01 |
| publisher | MRE Press |
| record_format | Article |
| series | Journal of Men's Health |
| spelling | doaj.art-374b73f778754d04a88578224bcfaa2a2024-02-03T14:44:47ZengMRE PressJournal of Men's Health1875-68592023-03-0119372110.22514/jomh.2023.026S1875-6867(23)00484-0The potential of mobile health applications to improve couples’ fertility: a systematic review and meta-analysis of randomized controlled trialsYing Li0Wan-jia Shen1Xiao-lin Wu2Xian-wen Jin3Department of Reproductive Endocrinology, Women’s Hospital, School of Medicine, Zhejiang University, 310006 Hangzhou, Zhejiang, ChinaDepartment of Reproductive Endocrinology, Women’s Hospital, School of Medicine, Zhejiang University, 310006 Hangzhou, Zhejiang, ChinaDepartment of Reproductive Endocrinology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, 322000 YiWu, Zhejiang, ChinaDepartment of Reproductive Endocrinology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, 322000 YiWu, Zhejiang, ChinaThe purpose of this systematic review was to examine the safety and effectiveness of mobile health applications in couples with infertility. Nineteen databases were searched from their inception to August 2022. Only randomized controlled trials (RCTs) in which mobile health was used as an intervention in infertile couples were included. A quantitative analysis of RCTs was employed using RevMan software. Study selection, data extraction and validation were performed by two independent reviewers according to the guidelines. The Cochrane criteria for risk-of-bias were used to evaluate the methodological quality of the trials. Eight RCTs met the inclusion criteria. Among the eight RCTs, two RCTs were from the Netherlands and the remaining six RCTs were from China. Meta-analysis showed that mobile health interventions in infertile couples in China were found to be superior to usual care in terms of clinical pregnancy rate (p = 0.001), psychological status (SAS (Self-Rating Anxiety Scale): p < 0.001; SDS (Self-Rating Depression Scale) p < 0.001;), infertility knowledge levels (p < 0.001), quality of life (p < 0.001), and serum levels of 5-hydroxytryptamine (p < 0.001). The effects on intervention groups using mobile health interventions in the Netherlands were not superior to the control groups that used usual care in terms of improving dietary factors (p > 0.05). In general, the positive effect of mobile health on improving clinical pregnancy rate, psychological status, infertility knowledge levels, quality of life and satisfaction with information was better than that of usual care. Mobile health interventions could be a viable supplement to the usual care for infertile couples. However, more high-quality RCTs need to be included in the future to provide additional evidence of the positive effects of mobile health in infertile couples.https://oss.jomh.org/files/article/20230330-65/pdf/JOMH15968.pdfmobile healthinfertilitysystematic review |
| spellingShingle | Ying Li Wan-jia Shen Xiao-lin Wu Xian-wen Jin The potential of mobile health applications to improve couples’ fertility: a systematic review and meta-analysis of randomized controlled trials Journal of Men's Health mobile health infertility systematic review |
| title | The potential of mobile health applications to improve couples’
fertility: a systematic review and meta-analysis of randomized controlled trials |
| title_full | The potential of mobile health applications to improve couples’
fertility: a systematic review and meta-analysis of randomized controlled trials |
| title_fullStr | The potential of mobile health applications to improve couples’
fertility: a systematic review and meta-analysis of randomized controlled trials |
| title_full_unstemmed | The potential of mobile health applications to improve couples’
fertility: a systematic review and meta-analysis of randomized controlled trials |
| title_short | The potential of mobile health applications to improve couples’
fertility: a systematic review and meta-analysis of randomized controlled trials |
| title_sort | potential of mobile health applications to improve couples fertility a systematic review and meta analysis of randomized controlled trials |
| topic | mobile health infertility systematic review |
| url | https://oss.jomh.org/files/article/20230330-65/pdf/JOMH15968.pdf |
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