Co-administration of herbal inhibitors of P-glycoprotein with renal drugs enhance their bioavailability– In silico approach
Introduction: Multidrug resistance (MDR) is primarily associated with reduced intracellular drug accumulation owing to overexpression of p-glycoprotein, an active efflux transporter. Competitive inhibition or allosteric modulation of p-glycoprotein may alter the pharmacokinetics of the drugs that se...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Shahrekord University of Medical Sciences
2023-04-01
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| Series: | Journal of HerbMed Pharmacology |
| Subjects: | |
| Online Access: | http://herbmedpharmacol.com/PDF/jhp-12-241.pdf |