Flash glucose monitoring in subjects with diabetes on hemodialysis: A pilot study
Background: In patients with diabetes related end-stage renal disease (ESRD) on hemodialysis, blood glucose management can be challenging due to the kinetics of glucose and insulin in addition to other factors. The glucose monitoring systems which measure glucose levels continuously may be useful to...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Indian Journal of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2018;volume=22;issue=6;spage=848;epage=851;aulast=Javherani |
| _version_ | 1818969470972985344 |
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| author | Rajesh S Javherani Vedavati B Purandare Anjali A Bhatt Suganthi S Kumaran Mehmood G Sayyad Ambika G Unnikrishnan |
| author_facet | Rajesh S Javherani Vedavati B Purandare Anjali A Bhatt Suganthi S Kumaran Mehmood G Sayyad Ambika G Unnikrishnan |
| author_sort | Rajesh S Javherani |
| collection | DOAJ |
| description | Background: In patients with diabetes related end-stage renal disease (ESRD) on hemodialysis, blood glucose management can be challenging due to the kinetics of glucose and insulin in addition to other factors. The glucose monitoring systems which measure glucose levels continuously may be useful to study the glucose profile of patients with diabetes undergoing hemodialysis. Our study is designed to use ambulatory glucose profile to study the glucose pattern – during, before, and after a session of hemodialysis. Materials and Methods: Ten patients with type 2 diabetes with ESRD undergoing hemodialysis were recruited. Forty-eight glucose readings were recorded in a 12-h period which included 4 h each prior, during, and after the dialysis session with a flash glucose monitor (FreeStyle Libre-pro). The same 12 h time frame was also monitored on a non-dialysis day. Results: On the day of dialysis, the mean glucose level was significantly lower (P = 0.013) compared to the day without dialysis (95 ± 12.7 mg/dl vs 194 ± 76.8 mg/dl). As compared to the pre-dialysis period, the mean blood glucose levels during dialysis were lower (P = 0.004). As compared to the dialysis period, the mean blood glucose levels in the post-dialysis period were higher but did not reach statistical significance. Conclusion: In our study, subjects with type 2 diabetes on hemodialysis had lower glucose levels on the day of dialysis compared to non-dialysis day. Glucose levels showed a fall during hemodialysis and then a rise to higher levels after dialysis. |
| first_indexed | 2024-12-20T14:21:06Z |
| format | Article |
| id | doaj.art-3750be4b3fbb4c1f9246d54acad1014c |
| institution | Directory Open Access Journal |
| issn | 2230-8210 |
| language | English |
| last_indexed | 2024-12-20T14:21:06Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Endocrinology and Metabolism |
| spelling | doaj.art-3750be4b3fbb4c1f9246d54acad1014c2022-12-21T19:37:56ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102018-01-0122684885110.4103/ijem.IJEM_520_18Flash glucose monitoring in subjects with diabetes on hemodialysis: A pilot studyRajesh S JavheraniVedavati B PurandareAnjali A BhattSuganthi S KumaranMehmood G SayyadAmbika G UnnikrishnanBackground: In patients with diabetes related end-stage renal disease (ESRD) on hemodialysis, blood glucose management can be challenging due to the kinetics of glucose and insulin in addition to other factors. The glucose monitoring systems which measure glucose levels continuously may be useful to study the glucose profile of patients with diabetes undergoing hemodialysis. Our study is designed to use ambulatory glucose profile to study the glucose pattern – during, before, and after a session of hemodialysis. Materials and Methods: Ten patients with type 2 diabetes with ESRD undergoing hemodialysis were recruited. Forty-eight glucose readings were recorded in a 12-h period which included 4 h each prior, during, and after the dialysis session with a flash glucose monitor (FreeStyle Libre-pro). The same 12 h time frame was also monitored on a non-dialysis day. Results: On the day of dialysis, the mean glucose level was significantly lower (P = 0.013) compared to the day without dialysis (95 ± 12.7 mg/dl vs 194 ± 76.8 mg/dl). As compared to the pre-dialysis period, the mean blood glucose levels during dialysis were lower (P = 0.004). As compared to the dialysis period, the mean blood glucose levels in the post-dialysis period were higher but did not reach statistical significance. Conclusion: In our study, subjects with type 2 diabetes on hemodialysis had lower glucose levels on the day of dialysis compared to non-dialysis day. Glucose levels showed a fall during hemodialysis and then a rise to higher levels after dialysis.http://www.ijem.in/article.asp?issn=2230-8210;year=2018;volume=22;issue=6;spage=848;epage=851;aulast=JavheraniAmbulatory glucose profileend-stage renal diseaseglycemic variabilityhypoglycemia |
| spellingShingle | Rajesh S Javherani Vedavati B Purandare Anjali A Bhatt Suganthi S Kumaran Mehmood G Sayyad Ambika G Unnikrishnan Flash glucose monitoring in subjects with diabetes on hemodialysis: A pilot study Indian Journal of Endocrinology and Metabolism Ambulatory glucose profile end-stage renal disease glycemic variability hypoglycemia |
| title | Flash glucose monitoring in subjects with diabetes on hemodialysis: A pilot study |
| title_full | Flash glucose monitoring in subjects with diabetes on hemodialysis: A pilot study |
| title_fullStr | Flash glucose monitoring in subjects with diabetes on hemodialysis: A pilot study |
| title_full_unstemmed | Flash glucose monitoring in subjects with diabetes on hemodialysis: A pilot study |
| title_short | Flash glucose monitoring in subjects with diabetes on hemodialysis: A pilot study |
| title_sort | flash glucose monitoring in subjects with diabetes on hemodialysis a pilot study |
| topic | Ambulatory glucose profile end-stage renal disease glycemic variability hypoglycemia |
| url | http://www.ijem.in/article.asp?issn=2230-8210;year=2018;volume=22;issue=6;spage=848;epage=851;aulast=Javherani |
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