Humoral and Cellular Immune Responses to Vector, Mix-and-Match, or mRNA Vaccines against SARS-CoV-2 and the Relationship between the Two Immune Responses

Humoral and Cellular Immune Responses to Vector, Mix-and-Match, or mRNA Vaccines against SARS-CoV-2 and the Relationship between the Two Immune Responses

ABSTRACT We investigated how differences in age, sex, or vaccine type can affect humoral and cellular immune responses after vaccination with vector (ChAdOx1 nCoV-19), mix-and-match (first, ChAdOx1 nCoV-19, and second, BNT162b2), or mRNA (BNT162b2 or mRNA-1273) vaccines against severe acute respirat...

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Bibliographic Details
Main Authors: Minjeong Nam, Seung Gyu Yun, Sang-wook Kim, Chris Gunwoo Kim, Jae Hyun Cha, Cheonghwa Lee, Seunghyuk Kang, Seul Gi Park, Sun Bean Kim, Ki-Byung Lee, You-Seung Chung, Myung-Hyun Nam, Chang Kyu Lee, Yunjung Cho
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:Microbiology Spectrum
Subjects:
cellular immune responses
humoral immune responses
vector vaccine
mix-and-match vaccine
mRNA vaccine
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02495-21

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