A population-based survey of the epidemiology of symptom-defined gastroesophageal reflux disease: the Systematic Investigation of Gastrointestinal Diseases in China
<p>Abstract</p> <p>Background</p> <p>The epidemiology of gastroesophageal reflux disease (GERD) has yet to be investigated using the symptomatic threshold criteria recommended by the Montreal Definition. This study aimed to determine the prevalence of symptom-defined GE...
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| Format: | Article |
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BMC
2010-08-01
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| Series: | BMC Gastroenterology |
| Online Access: | http://www.biomedcentral.com/1471-230X/10/94 |
| _version_ | 1818363996146761728 |
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| author | He Jia Ma Xiuqiang Zhao Yanfang Wang Rui Yan Xiaoyan Yan Hong Yin Ping Kang Xiaoping Fang Jiqian Hao Yuantao Li Qiang Dent John Sung Joseph JY Zou Duowu Wallander Mari-Ann Johansson Saga Liu Wenbin Li Zhaoshen |
| author_facet | He Jia Ma Xiuqiang Zhao Yanfang Wang Rui Yan Xiaoyan Yan Hong Yin Ping Kang Xiaoping Fang Jiqian Hao Yuantao Li Qiang Dent John Sung Joseph JY Zou Duowu Wallander Mari-Ann Johansson Saga Liu Wenbin Li Zhaoshen |
| author_sort | He Jia |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>The epidemiology of gastroesophageal reflux disease (GERD) has yet to be investigated using the symptomatic threshold criteria recommended by the Montreal Definition. This study aimed to determine the prevalence of symptom-defined GERD across five regions of China, and to investigate variables associated with GERD.</p> <p>Methods</p> <p>A representative sample of 18 000 adults (aged 18-80 years) were selected equally from rural and urban areas in each region (n = 1800). According to the Montreal Definition, GERD is present when mild symptoms of heartburn and/or regurgitation occur on ≥2 days a week, or moderate-to-severe symptoms of heartburn and/or regurgitation occur on ≥1 day a week.</p> <p>Results</p> <p>In total, 16 091 participants completed the survey (response rate: 89.4%) and 16 078 responses were suitable for analysis. Applying the Montreal criteria, the prevalence of symptom-defined GERD was 3.1% and varied significantly (<it>p </it>< 0.001) among the five regions (from 1.7% in Guangzhou to 5.1% in Wuhan) and between rural and urban populations (3.8% vs 2.4%). Factors significantly associated with GERD included living in a rural area and a family history of gastrointestinal diseases.</p> <p>Conclusions</p> <p>This population-based survey found that the prevalence of symptom-defined GERD in China was 3.1%, which is lower than that found in Western countries.</p> |
| first_indexed | 2024-12-13T21:57:20Z |
| format | Article |
| id | doaj.art-37528e4e21b147a8975b772793355cdf |
| institution | Directory Open Access Journal |
| issn | 1471-230X |
| language | English |
| last_indexed | 2024-12-13T21:57:20Z |
| publishDate | 2010-08-01 |
| publisher | BMC |
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| series | BMC Gastroenterology |
| spelling | doaj.art-37528e4e21b147a8975b772793355cdf2022-12-21T23:30:06ZengBMCBMC Gastroenterology1471-230X2010-08-011019410.1186/1471-230X-10-94A population-based survey of the epidemiology of symptom-defined gastroesophageal reflux disease: the Systematic Investigation of Gastrointestinal Diseases in ChinaHe JiaMa XiuqiangZhao YanfangWang RuiYan XiaoyanYan HongYin PingKang XiaopingFang JiqianHao YuantaoLi QiangDent JohnSung Joseph JYZou DuowuWallander Mari-AnnJohansson SagaLiu WenbinLi Zhaoshen<p>Abstract</p> <p>Background</p> <p>The epidemiology of gastroesophageal reflux disease (GERD) has yet to be investigated using the symptomatic threshold criteria recommended by the Montreal Definition. This study aimed to determine the prevalence of symptom-defined GERD across five regions of China, and to investigate variables associated with GERD.</p> <p>Methods</p> <p>A representative sample of 18 000 adults (aged 18-80 years) were selected equally from rural and urban areas in each region (n = 1800). According to the Montreal Definition, GERD is present when mild symptoms of heartburn and/or regurgitation occur on ≥2 days a week, or moderate-to-severe symptoms of heartburn and/or regurgitation occur on ≥1 day a week.</p> <p>Results</p> <p>In total, 16 091 participants completed the survey (response rate: 89.4%) and 16 078 responses were suitable for analysis. Applying the Montreal criteria, the prevalence of symptom-defined GERD was 3.1% and varied significantly (<it>p </it>< 0.001) among the five regions (from 1.7% in Guangzhou to 5.1% in Wuhan) and between rural and urban populations (3.8% vs 2.4%). Factors significantly associated with GERD included living in a rural area and a family history of gastrointestinal diseases.</p> <p>Conclusions</p> <p>This population-based survey found that the prevalence of symptom-defined GERD in China was 3.1%, which is lower than that found in Western countries.</p>http://www.biomedcentral.com/1471-230X/10/94 |
| spellingShingle | He Jia Ma Xiuqiang Zhao Yanfang Wang Rui Yan Xiaoyan Yan Hong Yin Ping Kang Xiaoping Fang Jiqian Hao Yuantao Li Qiang Dent John Sung Joseph JY Zou Duowu Wallander Mari-Ann Johansson Saga Liu Wenbin Li Zhaoshen A population-based survey of the epidemiology of symptom-defined gastroesophageal reflux disease: the Systematic Investigation of Gastrointestinal Diseases in China BMC Gastroenterology |
| title | A population-based survey of the epidemiology of symptom-defined gastroesophageal reflux disease: the Systematic Investigation of Gastrointestinal Diseases in China |
| title_full | A population-based survey of the epidemiology of symptom-defined gastroesophageal reflux disease: the Systematic Investigation of Gastrointestinal Diseases in China |
| title_fullStr | A population-based survey of the epidemiology of symptom-defined gastroesophageal reflux disease: the Systematic Investigation of Gastrointestinal Diseases in China |
| title_full_unstemmed | A population-based survey of the epidemiology of symptom-defined gastroesophageal reflux disease: the Systematic Investigation of Gastrointestinal Diseases in China |
| title_short | A population-based survey of the epidemiology of symptom-defined gastroesophageal reflux disease: the Systematic Investigation of Gastrointestinal Diseases in China |
| title_sort | population based survey of the epidemiology of symptom defined gastroesophageal reflux disease the systematic investigation of gastrointestinal diseases in china |
| url | http://www.biomedcentral.com/1471-230X/10/94 |
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