Developing a Neuroimaging Biomarker for Amyotrophic Lateral Sclerosis: Multi-Center Data Sharing and the Road to a “Global Cohort”

Developing a Neuroimaging Biomarker for Amyotrophic Lateral Sclerosis: Multi-Center Data Sharing and the Road to a “Global Cohort”

Neuroimaging in Amyotrophic Lateral Sclerosis (ALS) has steadily evolved from an academic exercise to a powerful clinical tool for detecting and following pathological change. Nevertheless, significant challenges need to be addressed for the translation of neuroimaging as a robust outcome-metric and...

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Bibliographic Details
Main Authors: Robert Steinbach, Nayana Gaur, Beatrice Stubendorff, Otto W. Witte, Julian Grosskreutz
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Neurology
Subjects:
amyotrophic lateral sclerosis
MRI
data-sharing
NiSALS
quality-control
harmonization
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.01055/full

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