Field-In-Field Plan Versus Tangential Wedged Beam Plan in Chest Wall Radiotherapy of Post-Mastectomy Patients: Treatment Planning Study
Introduction: In this study, dose distribution of the chest wall in post-mastectomy breast cancer patients was evaluated and compared in the tangential wedged beam (TWB) and field-in-field (FIF) plans. Materials and Methods: Thirty-six patients with left-sided breast cancer were enrolled in this stu...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2017-12-01
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| Series: | Iranian Journal of Medical Physics |
| Subjects: | |
| Online Access: | http://ijmp.mums.ac.ir/article_9164_1b68cb00c9d9b176e2d81ba1125980f8.pdf |
| _version_ | 1819262589116350464 |
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| author | Mehran Yarahmadi bahar faramarzi abbas haghparast zeinab saalehi |
| author_facet | Mehran Yarahmadi bahar faramarzi abbas haghparast zeinab saalehi |
| author_sort | Mehran Yarahmadi |
| collection | DOAJ |
| description | Introduction: In this study, dose distribution of the chest wall in post-mastectomy breast cancer patients was evaluated and compared in the tangential wedged beam (TWB) and field-in-field (FIF) plans.
Materials and Methods: Thirty-six patients with left-sided breast cancer were enrolled in this study. The FIF and TWB plans were generated for each patient to compare dosimetric parameters of the chest wall. The maximum dose (Dmax), homogeneity index (HI), conformity index (CI), and uniformity index (UI) were defined and used for comparison of the dosimetric parameters of the planning target volume (PTV) in both FIF and TWB plans. The percentage of volumes receiving at least 10, 20, 30, and 40 Gy of the left lung and 5, 10, 20, 25 and 30 Gy of the heart were used to compare the dosimetric results of the organs at risk. Statistical analysis was performed using SPSS, version 20.
Results: The FIF plan had significantly lower HI (P=0.000) than the TWB plan, indicating that the FIF plan was better than the TWB plan in PTV. The V40lung (15.36±4.35 vs. 18.37±4.42) and V30heart (8.15±3.75 vs. 10.94±3.94; P=0.000) were significantly lower in the FIF plan than in the TWB plan. In addition, the monitor unit (MU) was significantly lower in the FIF plan than in the TWB plan (227.76 vs. 323.59; P=0.000).
Conclusion: The FIF plan significantly reduced the dose volume of the left lung and heart in post-mastectomy radiotherapy compared to the TWB plan. Therefore, the FIF plan is recommended for this purpose. |
| first_indexed | 2024-12-23T20:00:06Z |
| format | Article |
| id | doaj.art-37566fde5aef49f6a60c512e0d589d77 |
| institution | Directory Open Access Journal |
| issn | 2345-3672 2345-3672 |
| language | English |
| last_indexed | 2024-12-23T20:00:06Z |
| publishDate | 2017-12-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Medical Physics |
| spelling | doaj.art-37566fde5aef49f6a60c512e0d589d772022-12-21T17:33:06ZengMashhad University of Medical SciencesIranian Journal of Medical Physics2345-36722345-36722017-12-0114425726310.22038/ijmp.2017.22982.12239164Field-In-Field Plan Versus Tangential Wedged Beam Plan in Chest Wall Radiotherapy of Post-Mastectomy Patients: Treatment Planning StudyMehran Yarahmadi0bahar faramarzi1abbas haghparast2zeinab saalehi3Medical Physics Dept., Kurdistan University of Medical Sciences, Sanandaj, Iran.Department of Medical Physics, School of medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.Department of Medical Physics, Faculty of Medicine, Kermanshah, Iran.Tohid Hospital, Department of Radiotherapy, Kurdistan University of Medical Sciences, Sanandaj, Iran.Introduction: In this study, dose distribution of the chest wall in post-mastectomy breast cancer patients was evaluated and compared in the tangential wedged beam (TWB) and field-in-field (FIF) plans. Materials and Methods: Thirty-six patients with left-sided breast cancer were enrolled in this study. The FIF and TWB plans were generated for each patient to compare dosimetric parameters of the chest wall. The maximum dose (Dmax), homogeneity index (HI), conformity index (CI), and uniformity index (UI) were defined and used for comparison of the dosimetric parameters of the planning target volume (PTV) in both FIF and TWB plans. The percentage of volumes receiving at least 10, 20, 30, and 40 Gy of the left lung and 5, 10, 20, 25 and 30 Gy of the heart were used to compare the dosimetric results of the organs at risk. Statistical analysis was performed using SPSS, version 20. Results: The FIF plan had significantly lower HI (P=0.000) than the TWB plan, indicating that the FIF plan was better than the TWB plan in PTV. The V40lung (15.36±4.35 vs. 18.37±4.42) and V30heart (8.15±3.75 vs. 10.94±3.94; P=0.000) were significantly lower in the FIF plan than in the TWB plan. In addition, the monitor unit (MU) was significantly lower in the FIF plan than in the TWB plan (227.76 vs. 323.59; P=0.000). Conclusion: The FIF plan significantly reduced the dose volume of the left lung and heart in post-mastectomy radiotherapy compared to the TWB plan. Therefore, the FIF plan is recommended for this purpose.http://ijmp.mums.ac.ir/article_9164_1b68cb00c9d9b176e2d81ba1125980f8.pdfBreast CancerHigh-Energy X-RayField-In-Field TechniqueTreatment PlanningTWB Plan |
| spellingShingle | Mehran Yarahmadi bahar faramarzi abbas haghparast zeinab saalehi Field-In-Field Plan Versus Tangential Wedged Beam Plan in Chest Wall Radiotherapy of Post-Mastectomy Patients: Treatment Planning Study Iranian Journal of Medical Physics Breast Cancer High-Energy X-Ray Field-In-Field Technique Treatment Planning TWB Plan |
| title | Field-In-Field Plan Versus Tangential Wedged Beam Plan in Chest Wall Radiotherapy of Post-Mastectomy Patients: Treatment Planning Study |
| title_full | Field-In-Field Plan Versus Tangential Wedged Beam Plan in Chest Wall Radiotherapy of Post-Mastectomy Patients: Treatment Planning Study |
| title_fullStr | Field-In-Field Plan Versus Tangential Wedged Beam Plan in Chest Wall Radiotherapy of Post-Mastectomy Patients: Treatment Planning Study |
| title_full_unstemmed | Field-In-Field Plan Versus Tangential Wedged Beam Plan in Chest Wall Radiotherapy of Post-Mastectomy Patients: Treatment Planning Study |
| title_short | Field-In-Field Plan Versus Tangential Wedged Beam Plan in Chest Wall Radiotherapy of Post-Mastectomy Patients: Treatment Planning Study |
| title_sort | field in field plan versus tangential wedged beam plan in chest wall radiotherapy of post mastectomy patients treatment planning study |
| topic | Breast Cancer High-Energy X-Ray Field-In-Field Technique Treatment Planning TWB Plan |
| url | http://ijmp.mums.ac.ir/article_9164_1b68cb00c9d9b176e2d81ba1125980f8.pdf |
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