Advances in Molecular Imaging with Ultrasound
Ultrasound imaging has long demonstrated utility in the study and measurement of anatomic features and noninvasive observation of blood flow. Within the last decade, advances in molecular biology and contrast agents have allowed researchers to use ultrasound to detect changes in the expression of mo...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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SAGE Publications
2010-05-01
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| Series: | Molecular Imaging |
| Online Access: | https://doi.org/10.2310/7290.2010.00022 |
| _version_ | 1797288627341885440 |
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| author | Ryan Gessner Paul A. Dayton |
| author_facet | Ryan Gessner Paul A. Dayton |
| author_sort | Ryan Gessner |
| collection | DOAJ |
| description | Ultrasound imaging has long demonstrated utility in the study and measurement of anatomic features and noninvasive observation of blood flow. Within the last decade, advances in molecular biology and contrast agents have allowed researchers to use ultrasound to detect changes in the expression of molecular markers on the vascular endothelium and other intravascular targets. This new technology, referred to as ultrasonic molecular imaging, is still in its infancy. However, in preclinical studies, ultrasonic molecular imaging has shown promise in assessing angiogenesis, inflammation, and thrombus. In this review, we discuss recent advances in microbubble-type contrast agent development, ultrasound technology, and signal processing strategies that have the potential to substantially improve the capabilities and utility of ultrasonic molecular imaging. |
| first_indexed | 2024-03-07T18:52:13Z |
| format | Article |
| id | doaj.art-37627ce8daee4e0997cffd77300ba0e7 |
| institution | Directory Open Access Journal |
| issn | 1536-0121 |
| language | English |
| last_indexed | 2024-03-07T18:52:13Z |
| publishDate | 2010-05-01 |
| publisher | SAGE Publications |
| record_format | Article |
| series | Molecular Imaging |
| spelling | doaj.art-37627ce8daee4e0997cffd77300ba0e72024-03-02T01:06:53ZengSAGE PublicationsMolecular Imaging1536-01212010-05-01910.2310/7290.2010.0002210.2310_7290.2010.00022Advances in Molecular Imaging with UltrasoundRyan GessnerPaul A. DaytonUltrasound imaging has long demonstrated utility in the study and measurement of anatomic features and noninvasive observation of blood flow. Within the last decade, advances in molecular biology and contrast agents have allowed researchers to use ultrasound to detect changes in the expression of molecular markers on the vascular endothelium and other intravascular targets. This new technology, referred to as ultrasonic molecular imaging, is still in its infancy. However, in preclinical studies, ultrasonic molecular imaging has shown promise in assessing angiogenesis, inflammation, and thrombus. In this review, we discuss recent advances in microbubble-type contrast agent development, ultrasound technology, and signal processing strategies that have the potential to substantially improve the capabilities and utility of ultrasonic molecular imaging.https://doi.org/10.2310/7290.2010.00022 |
| spellingShingle | Ryan Gessner Paul A. Dayton Advances in Molecular Imaging with Ultrasound Molecular Imaging |
| title | Advances in Molecular Imaging with Ultrasound |
| title_full | Advances in Molecular Imaging with Ultrasound |
| title_fullStr | Advances in Molecular Imaging with Ultrasound |
| title_full_unstemmed | Advances in Molecular Imaging with Ultrasound |
| title_short | Advances in Molecular Imaging with Ultrasound |
| title_sort | advances in molecular imaging with ultrasound |
| url | https://doi.org/10.2310/7290.2010.00022 |
| work_keys_str_mv | AT ryangessner advancesinmolecularimagingwithultrasound AT pauladayton advancesinmolecularimagingwithultrasound |