Granulomatosis with Polyangiitis Restricted to the Back Muscle: The First Case Report
Granulomatosis with polyangiitis (GPA) is an autoimmune disease which is a type of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis that frequently affects the lungs and kidneys. However, GPA limited to a single organ has also been reported. A 71-year-old man was admitted for back pa...
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MDPI AG
2020-08-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1010-660X/56/9/431 |
| _version_ | 1797707913403301888 |
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| author | Yu-Mi Lee Sang Wan Chung |
| author_facet | Yu-Mi Lee Sang Wan Chung |
| author_sort | Yu-Mi Lee |
| collection | DOAJ |
| description | Granulomatosis with polyangiitis (GPA) is an autoimmune disease which is a type of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis that frequently affects the lungs and kidneys. However, GPA limited to a single organ has also been reported. A 71-year-old man was admitted for back pain and fever. We detected elevated levels of inflammatory markers and myeloperoxidase-ANCA. Magnetic resonance imaging indicated diffuse inflammation of the back and psoas muscles. Histology showed degenerated muscle fibers and granulomatosis vasculitis with mixed lymphoplasma cell infiltration. High-dose methylprednisolone therapy improved his symptoms. A final diagnosis of GPA limited to the muscles was made. |
| first_indexed | 2024-03-12T06:13:31Z |
| format | Article |
| id | doaj.art-3767f4df19d049079f15c7df7fa2c1b8 |
| institution | Directory Open Access Journal |
| issn | 1010-660X |
| language | English |
| last_indexed | 2024-03-12T06:13:31Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-3767f4df19d049079f15c7df7fa2c1b82023-09-03T02:46:36ZengMDPI AGMedicina1010-660X2020-08-015643143110.3390/medicina56090431Granulomatosis with Polyangiitis Restricted to the Back Muscle: The First Case ReportYu-Mi Lee0Sang Wan Chung1Division of Infectious Diseases, Department of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University School of Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, KoreaDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, KoreaGranulomatosis with polyangiitis (GPA) is an autoimmune disease which is a type of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis that frequently affects the lungs and kidneys. However, GPA limited to a single organ has also been reported. A 71-year-old man was admitted for back pain and fever. We detected elevated levels of inflammatory markers and myeloperoxidase-ANCA. Magnetic resonance imaging indicated diffuse inflammation of the back and psoas muscles. Histology showed degenerated muscle fibers and granulomatosis vasculitis with mixed lymphoplasma cell infiltration. High-dose methylprednisolone therapy improved his symptoms. A final diagnosis of GPA limited to the muscles was made.https://www.mdpi.com/1010-660X/56/9/431ANCA-associated vasculitisorgan limited vasculitisGPA |
| spellingShingle | Yu-Mi Lee Sang Wan Chung Granulomatosis with Polyangiitis Restricted to the Back Muscle: The First Case Report Medicina ANCA-associated vasculitis organ limited vasculitis GPA |
| title | Granulomatosis with Polyangiitis Restricted to the Back Muscle: The First Case Report |
| title_full | Granulomatosis with Polyangiitis Restricted to the Back Muscle: The First Case Report |
| title_fullStr | Granulomatosis with Polyangiitis Restricted to the Back Muscle: The First Case Report |
| title_full_unstemmed | Granulomatosis with Polyangiitis Restricted to the Back Muscle: The First Case Report |
| title_short | Granulomatosis with Polyangiitis Restricted to the Back Muscle: The First Case Report |
| title_sort | granulomatosis with polyangiitis restricted to the back muscle the first case report |
| topic | ANCA-associated vasculitis organ limited vasculitis GPA |
| url | https://www.mdpi.com/1010-660X/56/9/431 |
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