Development of an Amplicon Nanopore Sequencing Strategy for Detection of Mutations Conferring Intermediate Resistance to Vancomycin in Staphylococcus aureus Strains

Development of an Amplicon Nanopore Sequencing Strategy for Detection of Mutations Conferring Intermediate Resistance to Vancomycin in Staphylococcus aureus Strains

ABSTRACT Staphylococcus aureus is a major cause of bacteremia and other hospital-acquired infections. The cell-wall active antibiotic vancomycin is commonly used to treat both methicillin-resistant (MRSA) and sensitive (MSSA) infections. Vancomycin intermediate S. aureus (VISA) variants can arise th...

Full description

Bibliographic Details
Main Authors: Abraham G. Moller, Robert A. Petit, Michelle H. Davis, Timothy D. Read
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:Microbiology Spectrum
Subjects:
Staphylococcus aureus
amplicon sequencing
antibiotic resistance
clinical microbiology
diagnostics
genomics
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02728-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.02728-22

Similar Items