Immunologic cellular characteristics of the tumour microenvironment of hepatocellular carcinoma drive patient outcomes

Immunologic cellular characteristics of the tumour microenvironment of hepatocellular carcinoma drive patient outcomes

Abstract Background Anti-tumour immune competence has an impact in hepatocarcinogenesis and success of anti-cancer therapies. Tumour-infiltrating lymphocytes (TILs) and monocytes/macrophages (TAMs) are proposed to have significance in cancer. However, there is only limited data concerning their impa...

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Bibliographic Details
Main Authors: Georgi Atanasov, Karoline Dino, Katrin Schierle, Corinna Dietel, Gabriela Aust, Johann Pratschke, Daniel Seehofer, Moritz Schmelzle, Hans-Michael Hau
Format: Article
Language:English
Published: BMC 2019-06-01
Series:World Journal of Surgical Oncology
Subjects:
Hepatocellular carcinoma
Monocytes/macrophages
Tumour-infiltrating lymphocytes
M2 macrophages
Biomarkers
Prognosis
Online Access:http://link.springer.com/article/10.1186/s12957-019-1635-3

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