The impact of respiratory viruses on lung health after preterm birth
Children born preterm, less than 37 weeks’ gestation, are at increased risk of viral respiratory infections and associated complications both during their initial birth hospitalisation and in their first years following discharge. This increased burden of viral respiratory infections is likely to ha...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2018-01-01
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| Series: | European Clinical Respiratory Journal |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/20018525.2018.1487214 |
| _version_ | 1828415669165621248 |
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| author | Nada Townsi Ingrid A. Laing Graham L. Hall Shannon J. Simpson |
| author_facet | Nada Townsi Ingrid A. Laing Graham L. Hall Shannon J. Simpson |
| author_sort | Nada Townsi |
| collection | DOAJ |
| description | Children born preterm, less than 37 weeks’ gestation, are at increased risk of viral respiratory infections and associated complications both during their initial birth hospitalisation and in their first years following discharge. This increased burden of viral respiratory infections is likely to have long term implications for lung health and function in individuals born preterm, particularly those with bronchopulmonary dysplasia. Several hypotheses have been put forward to explain the association between early life viral respiratory infection and development of suboptimal lung health and function later in life following preterm birth. Although preterm infants with diminished lung function, particularly small airways, might be particularly susceptible to asthma and wheezing disorders following viral infection, there is evidence that respiratory viruses can activate number of inflammatory and airway re-modelling pathways. Therefore, the aim of this review is to highlight the perinatal and early life risk factors that may contribute to increased susceptibility to viral respiratory infections among preterm infants during early life and to understand how respiratory viral infection may influence the development of abnormal lung health and function later in life. |
| first_indexed | 2024-12-10T13:49:23Z |
| format | Article |
| id | doaj.art-377109f4017d4848a0b4e005137e6edb |
| institution | Directory Open Access Journal |
| issn | 2001-8525 |
| language | English |
| last_indexed | 2024-12-10T13:49:23Z |
| publishDate | 2018-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | European Clinical Respiratory Journal |
| spelling | doaj.art-377109f4017d4848a0b4e005137e6edb2022-12-22T01:46:14ZengTaylor & Francis GroupEuropean Clinical Respiratory Journal2001-85252018-01-015110.1080/20018525.2018.14872141487214The impact of respiratory viruses on lung health after preterm birthNada Townsi0Ingrid A. Laing1Graham L. Hall2Shannon J. Simpson3Telethon Kids InstituteTelethon Kids InstituteTelethon Kids InstituteTelethon Kids InstituteChildren born preterm, less than 37 weeks’ gestation, are at increased risk of viral respiratory infections and associated complications both during their initial birth hospitalisation and in their first years following discharge. This increased burden of viral respiratory infections is likely to have long term implications for lung health and function in individuals born preterm, particularly those with bronchopulmonary dysplasia. Several hypotheses have been put forward to explain the association between early life viral respiratory infection and development of suboptimal lung health and function later in life following preterm birth. Although preterm infants with diminished lung function, particularly small airways, might be particularly susceptible to asthma and wheezing disorders following viral infection, there is evidence that respiratory viruses can activate number of inflammatory and airway re-modelling pathways. Therefore, the aim of this review is to highlight the perinatal and early life risk factors that may contribute to increased susceptibility to viral respiratory infections among preterm infants during early life and to understand how respiratory viral infection may influence the development of abnormal lung health and function later in life.http://dx.doi.org/10.1080/20018525.2018.1487214Virusesrespiratory infectionpretermlunginfantsbronchopulmonary dysplasia |
| spellingShingle | Nada Townsi Ingrid A. Laing Graham L. Hall Shannon J. Simpson The impact of respiratory viruses on lung health after preterm birth European Clinical Respiratory Journal Viruses respiratory infection preterm lung infants bronchopulmonary dysplasia |
| title | The impact of respiratory viruses on lung health after preterm birth |
| title_full | The impact of respiratory viruses on lung health after preterm birth |
| title_fullStr | The impact of respiratory viruses on lung health after preterm birth |
| title_full_unstemmed | The impact of respiratory viruses on lung health after preterm birth |
| title_short | The impact of respiratory viruses on lung health after preterm birth |
| title_sort | impact of respiratory viruses on lung health after preterm birth |
| topic | Viruses respiratory infection preterm lung infants bronchopulmonary dysplasia |
| url | http://dx.doi.org/10.1080/20018525.2018.1487214 |
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