Human decidual macrophages and NK cells differentially express Toll-like receptors and display distinct cytokine profiles upon TLR stimulation.

Human decidual macrophages and NK cells differentially express Toll-like receptors and display distinct cytokine profiles upon TLR stimulation.

Maternofetal pathogen transmission is partially controlled at the level of the maternal uterine mucosa at the fetal implantation site (the decidua basalis), where maternal and fetal cells are in close contact. Toll-like receptors (TLRs) may play an important role in initiating rapid immune responses...

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Bibliographic Details
Main Authors: Marion eDuriez, Héloïse eQuillay, Yoann eMadec, Hicham eEl-Costa, Claude eCannou, Romain eMarlin, Claire ede Truchis, Mona eRahmati, Françoise eBarré-Sinoussi, Marie-Thérèse eNugeyre, Elisabeth eMenu
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Microbiology
Subjects:
Cytokines
Decidua
Macrophages
NK cells
TLR
maternofetal interface
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00316/full

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