A Parameter and complication to be followed in COVID-19 patients: creatine kinase and rhabdomyolysis

This study aims to reveal the relationship between imaging findings obtained from computed tomography (CT), and CK levels in addition to other biochemical parameters in individuals diagnosed with COVID-19. The study also aims to draw awareness to the fact that COVID-19 may have various organ involve...

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Main Authors: Nevsun Pihtili Tas, Selda Telo
Format: Article
Language:English
Published: Society of Turaz Bilim 2022-03-01
Series:Medicine Science
Subjects:
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=79574
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author Nevsun Pihtili Tas
Selda Telo
author_facet Nevsun Pihtili Tas
Selda Telo
author_sort Nevsun Pihtili Tas
collection DOAJ
description This study aims to reveal the relationship between imaging findings obtained from computed tomography (CT), and CK levels in addition to other biochemical parameters in individuals diagnosed with COVID-19. The study also aims to draw awareness to the fact that COVID-19 may have various organ involvements apart from the lung. Two hundred and thirty patients with CT findings indicating COVID-19, and 119 control subjects without COVID-19 diagnosis, who had CT scans for other reasons, were included in this retrospective study. The patients were divided into three groups as those with ground-glass opacity (GGO) on CT, those with signs of consolidation (CONS) on CT, and the control group with normal CT findings. Then, the imaging and laboratory findings of the patients were evaluated. Of the CT-positive patients, 113 were females and 117 were males. There was no statistically significant difference between the groups in terms of the age variable (p=0.43). Ground-glass opacities were found on CT findings in 113 (32.3%) patients, and consolidation findings were found in 117 (33.7%) patients. Serum CK levels were 162.6 (U/L) (13-765) in the group with GGO while these levels were 162 (U/L) (6-731) in the CONS group and 94.27 (U/L) (11-400) in the normal CT group. CK levels were statistically increased in GGO and CONS groups compared to the normal CT group (p=0.000). In the initial admission of the patients with COVID-19 diagnoses, all the laboratory parameters should be evaluated carefully, and risky patients should be followed up considering complications, such as myositis and rhabdomyolysis that may affect mortality. [Med-Science 2022; 11(1.000): 98-101]
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spelling doaj.art-377850083dab4303861e0188dde07df62024-02-03T06:40:36ZengSociety of Turaz BilimMedicine Science2147-06342022-03-011119810110.5455/medscience.2021.05.16279574A Parameter and complication to be followed in COVID-19 patients: creatine kinase and rhabdomyolysisNevsun Pihtili Tas0Selda Telo1Department of Physical Medicine and Rehabilitation, Elazig Fethi Sekin City Hospital, Elazig, Turkey. Department of Biochemistry, Faculty of Dentistry, Firat University, Elazig, TurkeyThis study aims to reveal the relationship between imaging findings obtained from computed tomography (CT), and CK levels in addition to other biochemical parameters in individuals diagnosed with COVID-19. The study also aims to draw awareness to the fact that COVID-19 may have various organ involvements apart from the lung. Two hundred and thirty patients with CT findings indicating COVID-19, and 119 control subjects without COVID-19 diagnosis, who had CT scans for other reasons, were included in this retrospective study. The patients were divided into three groups as those with ground-glass opacity (GGO) on CT, those with signs of consolidation (CONS) on CT, and the control group with normal CT findings. Then, the imaging and laboratory findings of the patients were evaluated. Of the CT-positive patients, 113 were females and 117 were males. There was no statistically significant difference between the groups in terms of the age variable (p=0.43). Ground-glass opacities were found on CT findings in 113 (32.3%) patients, and consolidation findings were found in 117 (33.7%) patients. Serum CK levels were 162.6 (U/L) (13-765) in the group with GGO while these levels were 162 (U/L) (6-731) in the CONS group and 94.27 (U/L) (11-400) in the normal CT group. CK levels were statistically increased in GGO and CONS groups compared to the normal CT group (p=0.000). In the initial admission of the patients with COVID-19 diagnoses, all the laboratory parameters should be evaluated carefully, and risky patients should be followed up considering complications, such as myositis and rhabdomyolysis that may affect mortality. [Med-Science 2022; 11(1.000): 98-101]http://www.ejmanager.com/fulltextpdf.php?mno=79574covid-19rhabdomyolysisconsolidationground-glass opacity
spellingShingle Nevsun Pihtili Tas
Selda Telo
A Parameter and complication to be followed in COVID-19 patients: creatine kinase and rhabdomyolysis
Medicine Science
covid-19
rhabdomyolysis
consolidation
ground-glass opacity
title A Parameter and complication to be followed in COVID-19 patients: creatine kinase and rhabdomyolysis
title_full A Parameter and complication to be followed in COVID-19 patients: creatine kinase and rhabdomyolysis
title_fullStr A Parameter and complication to be followed in COVID-19 patients: creatine kinase and rhabdomyolysis
title_full_unstemmed A Parameter and complication to be followed in COVID-19 patients: creatine kinase and rhabdomyolysis
title_short A Parameter and complication to be followed in COVID-19 patients: creatine kinase and rhabdomyolysis
title_sort parameter and complication to be followed in covid 19 patients creatine kinase and rhabdomyolysis
topic covid-19
rhabdomyolysis
consolidation
ground-glass opacity
url http://www.ejmanager.com/fulltextpdf.php?mno=79574
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