Congenital microtia patients: the genetically engineered exosomes released from porous gelatin methacryloyl hydrogel for downstream small RNA profiling, functional modulation of microtia chondrocytes and tissue-engineered ear cartilage regeneration

Congenital microtia patients: the genetically engineered exosomes released from porous gelatin methacryloyl hydrogel for downstream small RNA profiling, functional modulation of microtia chondrocytes and tissue-engineered ear cartilage regeneration

Abstract Background Mesenchymal stem cells (MSCs) exosomes were previously shown to be effective in articular cartilage repairing. However, whether MSCs exosomes promote mature cartilage formation of microtia chondrocytes and the underlying mechanism of action remains unknown. Additionally, some hur...

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Bibliographic Details
Main Authors: Jianguo Chen, Tianyu Huang, Ruiquan Liu, Chenyu Wang, Haiyue Jiang, Hengyun Sun
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Journal of Nanobiotechnology
Subjects:
Adipose-derived stem cells
Engineered exosomes
Microtia
Porous gelatin methacryloyl
Tissue-engineered ear cartilage
Online Access:https://doi.org/10.1186/s12951-022-01352-6

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