Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction

Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction

Nuclear factor erythroid-2-related factor-2 (Nrf2), the major transcriptional regulator in antioxidant response and cellular defense, had the vital effect on regulating osteogenic differentiation. Our previous study revealed that Nrf2 activation was involved in cyclic mechanical stress-stimulated os...

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Bibliographic Details
Main Authors:	Xun Xi, Zixuan Li, Hong Liu, Shuai Chen, Dongxu Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-01-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	nuclear factor erythroid-2-related factor-2 mechanical stress orthodontic tooth movement periodontal ligament osteogenic differentiation
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2021.816000/full

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