Significance of Cancer-Associated Fibroblasts in the Interactions of Cancer Cells with the Tumor Microenvironment of Heterogeneous Tumor Tissue

The tumor microenvironment (TME) plays a key role in cancer development and progression, as well as contributes to the therapeutic resistance and metastasis of cancer cells. The TME is heterogeneous and consists of multiple cell types, including cancer-associated fibroblasts (CAFs), endothelial cell...

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Bibliographic Details
Main Authors: Yoshimi Arima, Satoko Matsueda, Hideyuki Saya
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/9/2536

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