Fine-tuning of mast cell activation by FceRIbeta chain

Fine-tuning of mast cell activation by FceRIbeta chain

Mast cells play the key role in allergic reaction and disorders, being activated by the high affinity receptor for IgE, FceRI. There are two types of FceRI expressed on the cell surface of human mast cells, abg2 type and ag2　type (without b chain), while in mouse mast cells only the tetrameric abg2...

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Bibliographic Details
Main Authors: Chisei eRa, Satoshi eNunomura, Yoshimichi eOkayama
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Immunology
Subjects:
Signal Transduction
mast cell
FceRI
FceRIbeta chain
ITAM
Cross Talk
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00112/full

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