Novel application of one-step pooled molecular testing and maximum likelihood approaches to estimate the prevalence of malaria parasitaemia among rapid diagnostic test negative samples in western Kenya

Novel application of one-step pooled molecular testing and maximum likelihood approaches to estimate the prevalence of malaria parasitaemia among rapid diagnostic test negative samples in western Kenya

Abstract Background Detection of malaria parasitaemia in samples that are negative by rapid diagnostic tests (RDTs) requires resource-intensive molecular tools. While pooled testing using a two-step strategy provides a cost-saving alternative to the gold standard of individual sample testing, statis...

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Bibliographic Details
Main Authors: Monica P. Shah, Winnie Chebore, Robert H. Lyles, Kephas Otieno, Zhiyong Zhou, Mateusz Plucinski, Lance A. Waller, Wycliffe Odongo, Kim A. Lindblade, Simon Kariuki, Aaron M. Samuels, Meghna Desai, Rebecca M. Mitchell, Ya Ping Shi
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Malaria Journal
Subjects:
Pooled testing
Group testing
Subpatent malaria parasitemia
Online Access:https://doi.org/10.1186/s12936-022-04323-2

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