Novel modeling approach integrating population pharmacokinetics and interspecies scaling to predict human pharmacokinetics of the new anti-tuberculosis agent telacebec (Q203)
Telacebec is a new anti-tuberculosis agent with promising therapeutic activity and a favorable safety profile. This study aimed to characterize the pharmacokinetics of telacebec via interspecies scaling and population pharmacokinetic modeling for the prediction of human pharmacokinetics. Preclinical...
Main Authors: | Jeongjun Kim, Tae Hwan Kim, Jinho Choi, Kiyean Nam, Beom Soo Shin, Soyoung Shin |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-11-01
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Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332223012398 |
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