Irf3 polymorphism alters induction of interferon beta in response to Listeria monocytogenes infection.

Irf3 polymorphism alters induction of interferon beta in response to Listeria monocytogenes infection.

Genetic makeup of the host plays a significant role in the course and outcome of infection. Inbred strains of mice display a wide range of sensitivities to Listeria monocytogenes infection and thus serve as a good model for analysis of the effect of genetic polymorphism. The outcome of L. monocytoge...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Oleg Garifulin, Zanmei Qi, Haihong Shen, Sujatha Patnala, Michael R Green, Victor Boyartchuk
Format: Artikel
Sprache:English
Veröffentlicht: Public Library of Science (PLoS) 2007-09-01
Schriftenreihe:PLoS Genetics
Online Zugang:http://europepmc.org/articles/PMC1971118?pdf=render

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