Irf3 polymorphism alters induction of interferon beta in response to Listeria monocytogenes infection.

Irf3 polymorphism alters induction of interferon beta in response to Listeria monocytogenes infection.

Genetic makeup of the host plays a significant role in the course and outcome of infection. Inbred strains of mice display a wide range of sensitivities to Listeria monocytogenes infection and thus serve as a good model for analysis of the effect of genetic polymorphism. The outcome of L. monocytoge...

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Detalles Bibliográficos
Autores principales: Oleg Garifulin, Zanmei Qi, Haihong Shen, Sujatha Patnala, Michael R Green, Victor Boyartchuk
Formato: Artículo
Lenguaje:English
Publicado: Public Library of Science (PLoS) 2007-09-01
Colección:PLoS Genetics
Acceso en línea:http://europepmc.org/articles/PMC1971118?pdf=render

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