Irf3 polymorphism alters induction of interferon beta in response to Listeria monocytogenes infection.

Genetic makeup of the host plays a significant role in the course and outcome of infection. Inbred strains of mice display a wide range of sensitivities to Listeria monocytogenes infection and thus serve as a good model for analysis of the effect of genetic polymorphism. The outcome of L. monocytoge...

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Autori principali: Oleg Garifulin, Zanmei Qi, Haihong Shen, Sujatha Patnala, Michael R Green, Victor Boyartchuk
Natura: Articolo
Lingua:English
Pubblicazione: Public Library of Science (PLoS) 2007-09-01
Serie:PLoS Genetics
Accesso online:http://europepmc.org/articles/PMC1971118?pdf=render